نتایج جستجو برای: tme

تعداد نتایج: 1374  

2016
T. Watanabe K. Hata

Surgery for rectal cancer is associated with high rates of local recurrence compared with surgery for colonic cancer1. Total mesorectal excision (TME) is now accepted widely as an important contributor in reducing this specific risk2. As advocated by Heald and colleagues3, the mesorectal lymph nodes are excised wholly without disturbing the mesorectum, but even with this technique the local rec...

Journal: :European Journal of Medical Research 2010

2003
Fikru Tafesse

Comparative reactivities of three diaqua(tetraamine)Co(III) complexes towards hydrolysis of 4-nitrophenyl phosphate was undertaken. The results were contrasted with prussian blue promoted hydrolysis of 4-nitrophenyl phosphate. The tetraamineCobalt(III) complexes accelerated the hydrolytic reaction to varying degrees with the following reactivity order. [(tn)2Co(OH2)2] < [(trpn)Co(OH2)2] < [(tme...

1994
Peter Baumgartner

Theory Reasoning means to build-in certain knowledge about a problem domain into a deduction system or calculus, which is in our case model elimination. Several versions of theory model elimination (TME) calculi are presented and proven complete: on the one hand we have highly restricted versions of total and partial TME. These restrictions allow (1) to keep fewer path literals in extension ste...

2018
Shaolin Ma Sunila Pradeep Wei Hu Dikai Zhang Robert Coleman Anil Sood

Anti-angiogenic therapy has been demonstrated to increase progression-free survival in patients with many different solid cancers. Unfortunately, the benefit in overall survival is modest and the rapid emergence of drug resistance is a significant clinical problem. Over the last decade, several mechanisms have been identified to decipher the emergence of resistance. There is a multitude of chan...

Journal: :Science 2017
Andrew S Venteicher Itay Tirosh Christine Hebert Keren Yizhak Cyril Neftel Mariella G Filbin Volker Hovestadt Leah E Escalante McKenzie L Shaw Christopher Rodman Shawn M Gillespie Danielle Dionne Christina C Luo Hiranmayi Ravichandran Ravindra Mylvaganam Christopher Mount Maristela L Onozato Brian V Nahed Hiroaki Wakimoto William T Curry A John Iafrate Miguel N Rivera Matthew P Frosch Todd R Golub Priscilla K Brastianos Gad Getz Anoop P Patel Michelle Monje Daniel P Cahill Orit Rozenblatt-Rosen David N Louis Bradley E Bernstein Aviv Regev Mario L Suvà

Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as the composition of the tumor microenvironment (TME). We dissected these influences in isocitrate dehydrogenase (IDH)-mutant gliomas by combining 14,226 single-cell RNA sequencing (RNA-seq) profiles from 16 patient samples with bulk RNA-seq profiles from 165 patient samples. Differences in bulk profil...

2001
Jason Randolph Cooke Gerald A. Miller Daniel R. Phillips Stephen R. Sharpe

Light Front Field Theory Calculation of Deuteron Properties by Jason Randolph Cooke Chair of Supervisory Committee:Professor Gerald A. MillerDepartment of Physics Light front dynamics is a promising approach for solving bound state problems innuclear physics. It is also ideal for calculating the deuteron form factors at highmomentum transfers. However, in light-front dynamics ro...

2015
Rahul Bhome Marc D. Bullock Hajir A. Al Saihati Rebecca W. Goh John N. Primrose A. Emre Sayan Alex H. Mirnezami

It is well established that the tumor microenvironment (TME) contributes to cancer progression. Stromal cells can be divided into mesenchymal, vascular, and immune. Signaling molecules secreted by the tumor corrupts these cells to create "activated" stroma. Equally, the extracellular matrix (ECM) contributes to tumor development and invasion by forming a biologically active scaffold. In this re...

2011
Mitsugu Fujita Gary Kohanbash Wendy Fellows-Mayle Ronald L. Hamilton Yoshihiro Komohara Stacy A. Decker John R. Ohlfest Hideho Okada

Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract Epidemiological studies have highlighted associations between the regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) and reduced glioma risks in humans. Most NSAIDs function ...

Journal: :Cancer research 2012
Melody A Swartz Noriho Iida Edward W Roberts Sabina Sangaletti Melissa H Wong Fiona E Yull Lisa M Coussens Yves A DeClerck

The tumor microenvironment (TME) consists of cells, soluble factors, signaling molecules, extracellular matrix, and mechanical cues that can promote neoplastic transformation, support tumor growth and invasion, protect the tumor from host immunity, foster therapeutic resistance, and provide niches for dormant metastases to thrive. An American Association for Cancer Research (AACR) special confe...

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