Influenza is a major cause of respiratory infection and has a high mortality rate in the elderly. Neuraminidase (NA) on the surface of the influenza virus and bacterial trypsin-like proteases (TLP) play key roles in influenza virus infections. We investigated the effects of oral care on influenza, evaluating in particular the activities of NA and TLP in saliva, as they may contribute to an incr...

The aim of this study was to determine the efficacy of The Listening Program (TLP) in treating a child with pervasive developmental disorder-not otherwise specified (PDD-NOS). Using a single-subject case study design, one child with PDD-NOS was administered a 20-week TLP intervention focused on improving sensory processing and language function. Data collection included pre- and post-evaluation...

In high-consequence systems, there is a high cost associated with failure. Thus, there should be strong evidence that the systems will not fail in field. Such evidence cannot be obtained by traditional verification methods such as testing. Transformation-oriented programming (TOP) is a promising formal software development technique. In TOP, a source file that represents a correct formal specif...

Transient lunar phenomena (TLPs) have been reported for centuries, but their nature is largely unsettled and remains controversial. In this Paper I the database of TLP reports is subjected to a discriminating statistical filter robust against sites of spurious reports, and produces a restricted sample that may be largely reliable. This subset is highly correlated geographically with the catalog...

Time-lock puzzles are elegant protocols that enable a party to lock message such no one else can unlock it until certain time elapses. Nevertheless, existing schemes not suitable for the case where server is given multiple instances of puzzle scheme at once and must them different points in time. If naively used this setting, then has start solving all as soon receives them, ultimately imposes ...

The tension legs are the essential parts of platform-type (TLP-type) floating offshore wind turbine (FOWT) against extra buoyancy FOWT. Therefore, TLP-type FOWT will face risk leg failure. However, there seldom analyses on hydrodynamic response and failure performance with inclined legs. In this paper, a model was established using three-dimensional theory applied in motion conventional new arr...

The death receptor CD95/Fas can be activated by immune cells to kill cancer cells. shRNAs and siRNAs derived from CD95 or CD95 ligand (CD95L) are highly toxic to most cancer cells. We recently found that these sh/siRNAs kill cancer cells in the absence of the target by targeting the 3'UTRs of critical survival genes through canonical RNAi. We have named this unique form of off-target effect DIS...

A disturbance accommodating controller (DAC) to reject wind speed perturbations is applied on a 5MW wind turbine mounted on a tension leg platform (TLP). Multi-blade coordinate (MBC) transformation is used to address the periodicity of the floating wind turbine system. A method to apply DAC after applying MBC transformation is developed and several implementation options are presented. Simulati...

PAX5 is a member of the PAX family of developmental transcription factors with an important role in B-cell development. Its expression in normal adult tissue is limited to the hemopoietic system, but it is aberrantly expressed in a number of solid cancers and leukemias where it functions as an oncogene. We therefore hypothesized that anti-PAX5 immune responses could be used to target a number o...