Let a, b, k, and m be positive integers such that 1 ≤ a < b and 2 ≤ k ≤ (b + 1− m)/a. Let G = (V (G), E(G)) be a graph of order |G|. Suppose that |G| > (a + b)(k(a + b − 1) − 1)/b and |NG(x1) ∪ NG(x2) ∪ · · · ∪ NG(xk)| ≥ a|G|/(a+ b) for every independent set {x1, x2, . . . , xk} ⊆ V (G). Then for any subgraph H of G with m edges and δ(G−E(H)) ≥ a, G has an [a, b]-factor F such that E(H) ∩ E(F )...

Growing evidences indicated that Long noncoding RNAs (lncRNAs) played important roles in tumor initiation and progression. However, the function and mechnism of lncRNA ferritin heavy chain 1 pseudogene 3 (FTH1P3) remain unknown in uveal melanoma. We showed that the expression level of FTH1P3 was upregulated in uveal melanoma cell lines and tissues. Elevated expression of FTH1P3 promoted uveal m...

Malignant melanoma is highly lethal due to its aggressive invasive properties and metastatic dissemination. The transcription factor E2F1 is crucial for melanoma progression through poorly understood mechanisms. Here, we show that the miR-224/miR-452 cluster is significantly increased in advanced melanoma and invasive/ metastatic cell lines that express high levels of E2F1. miR-224/miR452 expre...

MicroRNAs (miRNAs) are between 19 and 25 mer non‑coding RNAs involved in cancer cell proliferation, apoptosis, stress responses and maintenance of stem cell potency. In the present study, miR‑224 was observed to be upregulated in colorectal cancer (CRC) tissue. Overexpression of miR‑224 facilitated proliferation of the CRC cell lines, HCT‑116 and SW‑480. Bioinformatics analysis revealed a putat...

The time course and dose dependency of the incidence of bone-sarcomas among 900 German patients treated with high doses of radium-224 is analysed in terms of a proportional hazards model with a log-normal dependency of time to tumor and a linear-quadratic dose relation. The deduced dose dependency agrees well with a previous analysis in terms of a non-parametric proportional hazards model, and ...

It is vital to develop a quick and reliable approach for nitrobenzene in gas phase detection. In this work, the quartz crystal microbalance (QCM) platform was used take advantage of porphyrin-based metal-organic frameworks (MOFs) PCN-224 as novel sensing material sensitive selective detection vapor. Besides, response time only 16 s achieved. Meanwhile, frequency shift sensor could be proportion...

La crise li&#233;e &#224; la pand&#233;mie de&#160;Covid-19 en France en&#160;2020 bouleverse l&#8217;organisation du travail et les relations professionnelles dans entreprises. Dans ce contexte, comit&#233;s sociaux &#233;conomiques&#160;(CSE), pourtant plupart des cas nouvellement instaur&#233;s depuis leur cr&#233;ation avec ordonnances 22&#160;septembre 2017, ont un r&#244;le important joue...

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The objective of this project is to analyze the performance of a class-based language model and compare it to the performance of traditional n-gram language models. Class-based language models are well-studied, as is the use of clustering to learn classes of words. However, it seems fairly standard across the literature to use hard-clustering i.e. assign each word to a single class and then to ...