BACKGROUND This study aimed to observe the effect of recruitment maneuver (RM) and post-RM ventilation at different tidal volume on lung vascular diastole endothelial function in rats with acute lung injury (ALI). METHODS A ALI rat model was produced by intravenous infusion of lipopolysaccharide (6 mg/ kg). Twenty-five rats were randomly divided into five groups: control group (n=5), ALI grou...

The theory of Battisti and Clarke (1982) to calculate analytically barotropic tidal currents across 'smooth' continental margin topography is shown to be valid near shore on 'nonsmooth' continental shelves. The theory includes longshore gradients and friction and produces formulae easily evaluated with coastal sea level data. The tidal currents across three such shelves (West Florida, south of ...

BACKGROUND Preoxygenation with tidal volume breathing for 3 min is commonly used technique. An end tidal expiratory oxygen concentration greater than 90% is considerd to be adequate for preoxygenation. The aim of this study was to check the effects of preoxygenation on elderly patients through the comparison with young patients during the 3 min tidal volume breathing technique. METHODS Sixty ...

INTRODUCTION Recent cohort studies have identified the use of large tidal volumes as a major risk factor for development of lung injury in mechanically ventilated patients without acute lung injury (ALI). We compared the effect of conventional with lower tidal volumes on pulmonary inflammation and development of lung injury in critically ill patients without ALI at the onset of mechanical venti...

In this study, the impacts of different ventilation modes on respiratory mechanics, blood gas and hemodynamics in elderly patients undergoing laparoscopic cholecystectomy (LC) were compared. 60 LC patients were divided into 3 groups: group L (low tidal volume), group L + P (low tidal volume + positive end expiratory pressure) and group C (large tidal volume). Endotracheal intubation was placed ...

Both isoproterenol and tidal fluctuations of muscle length inhibit active force development in activated airway smooth muscle. In this study, we show that length fluctuations in the range of amplitudes expected during quiet tidal breathing produce force inhibition that is equipotent with high concentrations of isoproterenol. Active force fell to 50% of its isometric value when the amplitude of ...