Techniques for the determination of thyroid function have become increasingly refined since the demonstration of the relation of basal oxygen consumption to thyroid activity 50 years ago. Newer methods include the determination of serum protein-bound iodine and various procedures using radioactive iodine. The latter include direct measurements of the accumulation in the thyroid gland of an admi...

The radioactive iodine has been used with great value as a diagnostic and therapeutic method in patients with differentiated thyroid carcinoma previously submitted to total thyroidectomy. False-positive whole-body scans may occur due to misinterpretation of the physiologic distribution of the radioisotope or lack of knowledge on the existence of other pathologies that could eventually present r...

Iodine plays a central role in thyroid physiology, being both a major constituent of thyroid hormones (THS) and a regulator of thyroid gland function. This review concerns those aspects of thyroid physiology in which significant advances have been made in recent years. We have known for decades that the thyroid gland concentrates iodine (I-) against an electrochemical gradient by a carrier-medi...

conclusions high prevalence of thyroid antibodies in euthyroid patients with pcos refers to the importance of investigation for thyroid autoimmune state in those patients. objectives the aim of this study was to evaluate the prevalence and levels of thyroid antibodies in euthyroid women with pcos in syria. patients and methods this study included 56 euthyroid women with pcos and 30 healthy wome...

abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...

The generic term thyrotoxicosis defines the clinical syndrome of hypermetabolism associated with excess amounts of circulating free thyroxine (T4) and (or) triiodothyronine (T3) concentrations, irrespective of the source of the excess hormones. The term hyperthyroidism is reserved for those patients with thyrotoxicosis caused by increased synthesis and secretion of thyroid hormones from the gla...

The results of this study has revealed a significant increase in I(131) uptake of cultivated thyroid gland in the media containing petroleum ether extract of Commiphora mukul. Besides, T(3) resin uptake, protein bound iodine as well as free thyroxine index in the media are also observed to be significantly (P 0.001) increased. When explants are cultivated in the media containing melatonin, ther...

administration of a precise amount of activity in thyroid gland radioiodine (¹³¹i) therapy is of prime importance. several methods for this purpose have been suggested and used over many years. in this paper, a method for required ¹³¹i activity calculation for each case has been proposed. major factors affecting ¹³¹i calculation such as gland volume, integral dose, and prescription index have b...

aim: thyroid scan with sestamibi is used for evaluation of thyroid nodules with the aim of increasing specificity before surgery. in this study we evaluated the role of sestamibi thyroid scan in candidates for thyroid surgery. methods and patients: during two years, 37 patients were studied with solitary thyroid nodules, referred for thyroid surgery due to malignant or suspicious fnab results (...

Abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. We report an 11 years old girl who developed central hypothyroidism and ACTH deficiency during the chemotherapy for CNS relapse of acute lymphoblastic leukemia before receiving radiotherapy. Keywords: Thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leu...