The substitution of gallic acid at the 3 position of (-)-epigallocatechin-3-O-gallate (EGCG) increased the inhibition against topoisomerase I from calf thymus gland and topoisomerase II from human placenta, and the substitution of a hydroxyl group at the 3' position increased the inhibition against the topoisomerase I. These results suggested that the 3 and 3' positions of the EGCG molecule pla...

Results: Of 179 attempted autotransplantations of parathyroid glands, parathyroid tissue was confirmed in 167 biopsy specimens (93.3%). Incorrect identification of parathyroid gland occurred in 12 instances. The tissue mistaken as parathyroid gland included fat in 6 cases, thyroid tissue in 4 cases, lymph node in 1 case, and thymus in 1 case. Transplantation of at least 1 parathyroid gland (ran...

Transplantable tumors, as a rule, develop more readily in young animals. A transplantable lymphatic leukemia of the rat, which has been under investigation in this laboratory (12), resembles the tumors in this respect. Animals from a susceptible strain, if inoculated under 5 months of age, prove susceptible in something over 95 per cent, while rats between 12 and 15 months of age develop the di...

The pathological and clinical (may I even say surgical ?) approach has thus furnished us with a working hypothesis on which the function of the thymus gland may eventually be elucidated. There are still many difficulties in the way of a final solution, and progress is likely to be slow. It may be thought safer to return for the present to Galen's belief that the thymus is just a cushion to prot...

We describe the case of a young female affected by a thymus teratoma coexisting with carcinoid tumor.

Deficits in neuroendocrine-immune system functioning, including alterations in pineal and thymic glands, contribute to aging-associated diseases. This study looks at ageing-associated alterations in pineal and thymic gland functioning evaluating common signaling molecules present in both human and animal pinealocytes and thymocytes: endocrine cell markers (melatonin, serotonin, pCREB, AANAT, CG...

The thymus is now considered a derivative of the immune system being, to greater extent, its central organ. Immunodeficiency states and dysregulation also depend on quality thymus, which may be determined both genetically by fetopathic approach as well due possibility mode intravital injuries, age-related involution over different periods life. Not accidentally, there are various morphometric b...