tlc screening and evaluation of antioxidant, antibacterial activity of onopordon macrocephalum by bioautography methodonopordon known as scotch thistle is a medicinal plant of the asteraceae family that is widely distributed in europe and asia, also it has many valuable medicinal properties as hypotensive and antitumor. thin layer chromatography (tlc) is wildly used in natural product extract a...

Silybin A (1), silybin B (2), and isosilybin A (3), three of the seven flavonolignans that constitute silymarin, an extract of the fruits of milk thistle (Silybum marianum), were detected for the first time from a fungal endophyte, Aspergillus iizukae, isolated from the surface-sterilized leaves of S. marianum. The flavonolignans were identified using a UPLC-PDA-HRMS-MS/MS method by matching re...

Diabetes mellitus is a metabolic disorder that results in hyperglycemia due to decreased insulin production or inefficient insulin utilization. This disease has been reported in animals, particularly in aged dogs. However, the disorder is much more prevalent in humans. Millions of people across the globe currently have diabetes and incidence rates are predicted to increase dramatically as the p...

The flavolignans silybin (1) and 2,3-dehydrosilybin (2) (Figure 1) were isolated from fruits of milk thistle [Silybum marianum (L). Gaertn.] cultivated in the Samara region (Russian Federation). 2,3-dehydrosilybin (2) for the first time in Russian Federation is described for the given plant. Silybin and 2,3-dehydrosilybin and also new preparation, a fluid extract of Silybum marianum fruits, hav...

The endophytic fungus Penicillium restrictum was isolated from the stems of a milk thistle (Silybum marianum) plant. In culture, the fungus produced distinct red guttates, which have been virtually uninvestigated, particularly from the standpoint of chemistry. Hence, this study examined the chemical mycology of P. restrictum and, in doing so, uncovered a series of both known and new polyhydroxy...

The number phytopathogenic micromycetes is determined in the seeds of such cultivated varieties cultural plant as soybeans, sunflowers, yellow mustard, buckwheat and thistle, which are grown by organic technology. It shown that differs significantly ranges from 0.2 to 1.3 thousand NCO/g seeds. depends on properties plants variety hybrid, characterized some certain set physiological biochemical ...

H. Fallah Huseini*, B. Larijani, R. Heshmat, H. Fakhrzadeh, B. Radjabipour, T. Toliat and Mohsin Raza Department of Pharmacology, Institute of Medicinal Plants, ACECR Tehran, Iran Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Department of Physiology, School of Medical Sci...

Women at high risk of developing breast cancer are prescribed selective estrogen response modulators, including raloxifene, as chemoprevention. Patients often seek complementary and alternative treatment modalities, including herbal products, to supplement prescribed medications. Milk thistle preparations, including silibinin and silymarin, are top-selling herbal products that may be consumed b...