The combination of chronic heart failure and metabolic syndrome is a common clinical case. Patients with this pathology belong to the group high cardiovascular risk, which explained by higher frequency severity traditional factors. Of particular interest use "L−BIOCOMPLEX (liposomal)" dietary supplement "Biolik" company (Kharkiv, Ukraine), available in liposomal form as set L−carnitine + thioct...

Abstract Supramolecular polymers are materials that exhibit a range of functionalities and thus find wide applicability. In this study, two natural low‐molecular‐weight compounds, thioctic acid ( TA ) phytic PA ), used to fabricate polymeric supramolecular structures. The coexistence dynamically covalently linked poly( hydrogen bond moieties result in copolymeric with different dynamic features...

Self-assembly of metallic nanoparticles were investigated for the development of field-enhanced chemical and biological detection devices with the capacity to achieve single-molecule level detection resulting from surface enhanced Raman scattering, associated with closely spaced noble metal nanostructures. Using chemical selfassembly, we attached monodisperse, colloidal gold nanoparticles on se...

The aim of the work. Theoretical and experimental substantiation a rational technology for obtaining preparation in form capsules based on uridine-5-monophosphate disodium salt, cytidine-5-monophosphate vitamin B6, thioctic acid magnesium lactate dihydrate, determination process parameters that can affect critical quality characteristics active pharmaceutical ingredients product establishing ac...

Alpha-lipoic acid (ALA, thioctic acid), a naturally-occurring essential dithiol compound, has become common ingredient in many pharmaceutical and food supplement products (FSP), used oxidative stress-dependent pathologies; oral bioavailability of ALA is limited by pharmacokinetic particularities that reduce its therapeutic efficacy-reduced solubility, lack gastric stability hepatic degradation,...