BACKGROUND Fast-acting insulin aspart (faster aspart) is insulin aspart set in a new formulation with faster initial absorption after subcutaneous administration. This study investigated the pharmacokinetic properties, including the absolute bioavailability, of faster aspart when administered subcutaneously in the abdomen, upper arm or thigh. METHODS In a randomised, open-label, crossover tri...

OBJECTIVE To examine associations between thigh circumference and incident cardiovascular disease and coronary heart disease and total mortality. DESIGN Prospective observational cohort study with Cox proportional hazards model and restricted cubic splines. SETTING Random subset of adults in Denmark. PARTICIPANTS 1436 men and 1380 women participating in the Danish MONICA project, examined...

In this paper we report investigations of the innervation of duplicated limb segments to test whether the addition of limb segments along the proximodistal axons could stimulate the growth of appropriate motoneurons into double occurrences of these muscles. Our evidence indicates that it does not. Using retrograde horseradish peroxidase nerve-tracing techniques and reconstructions of experiment...

Thigh subcutaneous emphysema is an usual orthopaedic presentation normally associated with musculoskeletal problems or penetrating wounds. But, sometimes it can be related to abdominal pathology. We present a case of subcutaneous emphysema of the thigh secondary to para-caecal abscess.

In 2016, an 85-year-old Belgian woman presented to our hospital with a 2 year history of fistulised collection in the root left thigh, associated weight loss (20 kg) and sweats, no evidence fever. She did not take any immunosuppressive drugs. Having previously worked as farmer, she had frequent contacts cattle dogs. frequently ate wild berries. travelling. Physical examination was unremarkable,...

objectives: knowledge about gender differences in intra-limb coordination during walking provides insight into the adaptability of central nervous system for controlling gait in older adults. we assessed the variability and phase dynamic of the intra-limb coordination in older men and women during walking. methods: twenty two older people, 11 female and 11 male, participated in this study. they...

OBJECTIVES Muscle volume in patients with muscle disease is an index of disease progression. The aim of this study was to demonstrate a new method of muscle volumetry using CT of thigh muscles. DESIGN Observational study. PARTICIPANTS (1) For muscle volumetry using CT and dual-energy X-ray absorptiometry (DXA), 13 patients with muscle disease participated. (2) For prospective CT volumetry, ...

BACKGROUND The higher risk of type 2 diabetes in persons with a high waist-to-hip ratio (WHR) or waist-to-thigh ratio (WTR) has mostly been attributed to increased visceral fat accumulation. However, smaller hip or thigh circumference may also explain the predictive value of the WHR or WTR for type 2 diabetes. OBJECTIVE This study considered prospectively the association of hip and thigh circ...

a few days and applied evaporating lotion and put extension from the'lower part of the thigh, keeping the leg straight with sand-bags. Examining again on 21st Jul)7, I found, to my surprise, a fluctuating and tympanitic tumour occupying Scarpa's triangle and the adjacent inner portion of the thigh. I at once thought of a femoral hernia, as there was a distinctly intestinal note over the swellin...

Figure 1. (a) Left medial thigh showing discoloration and swelling. Maximal pain to palpation was in the centrally marked area, but pain could be elicited as far back as the dotted lines. (b) Left medial thigh following surgical debridement down to viable fat, fascia, and muscle. DESCRIPTION A 28-year-old woman with a raised body mass index presented feeling unwell with a 16-hour history of inc...