Abstract Intermittent fasting blunts inflammation in asthma and rheumatoid arthritis, suggesting that may be exploited as an immune-modulatory intervention. However, mechanisms underpinning anti-inflammatory effects of remain poorly characterized. Here, we show humans is sufficient to blunt CD4+ T helper cell responsiveness. RNA-seq flow cytometric immunophenotyping peripheral blood mononuclear...

Sirtuin-1 (SirT1) is a nutrient-sensing deacetylase whose levels and activity increase with caloric restriction to preserve euglycemia and promote efficient energy utilization. Focusing on data obtained in vivo, we review how SirT1 orchestrates the adaptive response to fasting by stimulating hepatic gluconeogenesis and fatty acid oxidation, increasing circulating adiponectin levels and limiting...

the islamic fast during the month of ramadan is strictly observed worldwide by millions of muslims. ramadan is the 9th month of the islamic lunar calendar and fasting during ramadan is the religious duty of all healthy adult muslims. a whole month of intermittent fasting, from dawn to dusk, every year is particular only to islam and considering that islam has over 1.5 billion followers worldwid...

levels of both fasting blood sugar and glycosylated hemoglobin (HbA1c), the U.S. Centers for Disease Control and Prevention (CDC) estimated that 18.8 million people had diabetes mellitus and 79 million people had prediabetes in the United States in 2010.1,2 Diabetes mellitus is the seventh leading cause of death in the United States, as well as the leading cause of nontraumatic amputations, car...

background & objectives: annually, many muslims fast during the month of ramadan worldwide. this practice has different favorable medical and physiological effects, such as improved serum lipid profile and blood glucose level due to changes in diet and sleep patterns. it has also been hypothesized that ramadan fasting may affect the immune system. as reported, ramadan fasting can influence the ...

background and purpose: preoperative fast is the essential part of preoperative care for those patients who are candidates for elective surgery. fast prolongation results in side effects such as: sweating, irritability, decrease in blood sugar and restlessness. despite the noticeable changes in fasting guidelines and their application in many countries, it seems that in iran, these rules are no...

ramadan is one of the special months for muslims all over the world. during ramadan, able‐bodied muslims are abstained from eating, drinking and even smoking from dawn to sunset. in malaysia, the duration of fasting are normally around 13 hours at any time of the year as it is located near the equator. the altered food intake timing and long period of fasting do influence on eating behavior of ...

The two most prevalent causes of end-stage renal disease nowadays are thought to be diabetic mellitus (DM) and hypertension (ESRD). In addition discussing the function DM in ESRD, this study reviews glucose metabolism treatment hyperglycemia these patients. Although strict glycemic control ESRD patient survival were not significantly correlated numerous big trials, it is advised that prioritise...

Fibroblast growth factor (FGF)21 is an endocrine hormone that is expressed in multiple tissues and functions physiologically to maintain energy homeostasis. FGF21 is being pursued as a therapeutic target for diabetes and obesity because of its rapid and potent effects on improving insulin sensitivity. However, whether FGF21 enhances insulin sensitivity under physiologic conditions remains uncle...