نتایج جستجو برای: theranostic
تعداد نتایج: 2090 فیلتر نتایج به سال:
Based on statistics from the National Cancer Institute in US, rate of new cases cancer is 442.4 per 100,000 men and women year, more than one-third do not survive disease. diagnosis treatment are most important challenges modern medicine. The majority diagnosed at an early stage. However, possibility simultaneous application therapy (theranostics) will allow for acceleration effectiveness treat...
Nanomedicine research started exploring the combination of therapy and diagnostics, so-called theranostics, to offer a more flexible care with improved outcome. As magnetic nanoparticles show great potential in many diagnostic therapeutic applications, they are prime candidates be used theranostic setting. This perspective gives an overview state-of-the-art nanoparticle-based imaging techniques...
Prostate and breast cancer are the second most and most commonly diagnosed cancer in men and women worldwide, respectively. The American Cancer Society estimates that during 2016 in the USA around 430,000 individuals were diagnosed with one of these two types of cancers, and approximately 15% of them will die from the disease. In Europe, the rate of incidences and deaths are similar to those in...
Background In the present study, the tumor-specific, pH-responsive peptide H7K(R2)2-modified, theranostic liposome-containing paclitaxel (PTX) and superparamagnetic iron oxide nanoparticles (SPIO NPs), PTX/SPIO-SSL-H7K(R2)2, was prepared by using H7K(R2)2 as the targeting ligand, SPIO NPs as the magnetic resonance imaging (MRI) agent, PTX as antitumor drug. Methods The PTX/SPIO-SSL-H7K(R2)2 w...
Although tremendous efforts have been made on targeted drug delivery systems, current therapy outcomes still suffer from low circulating time and limited targeting efficiency. The integration of cell-mediated drug delivery and theranostic nanomedicine can potentially improve cancer management in both therapeutic and diagnostic applications. By taking advantage of innate immune cell's ability to...
Innovative and personalized therapeutic approaches result from the identification and control of individual aberrantly expressed genes at the transcriptional and post-transcriptional level. Therefore, it is of high interest to establish diagnostic, therapeutic and theranostic strategies at these levels. In the present study, we used the Diels-Alder Reaction with inverse electron demand (DAR(inv...
The paucity of clinical treatment data on rare tumors, such as mesenchymal chondrosarcoma (MCS), emphasizes the need in theranostic tools for these diseases. We put forward and validated a new theranostic method, combining tumor xenografts and mathematical models, and used it to suggest an improved treatment schedule for a particular MCS patient. Growth curves and gene expression analysis of xe...
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