Sympathetic nerve activity increases in the heart during cardiac failure. Here, we hypothesized that 1 integrins play a protective role in chronic -adrenergic receptor–stimulated cardiac myocyte apoptosis and heart failure. L-isoproterenol (iso; 400 g/kg per hour) was infused in a group of wild-type (WT) and 1 integrin heterozygous knockout (hKO) mice. Left ventricular structural and functional...

By means of EPR spectroscopy the behaviour of the vanadocene dichloride (I), Cp(2)VCl(2) (Cp=eta(5)-C(5)H(5)), in various deoxygenated and non-deoxygenated physiological media and therapeutic solution as well as in blood plasma and stabilized human blood was studied. On the basis of measured values of isotropic spectroscopic splitting factor g(iso) and isotropic hyperfine coupling constant A(is...

Problem statement: The International Organization for Standardization (ISO) published a set of international standards related to the software engineering, such as ISO 12207 and ISO 9126. However, there is a set of cross-references between these two standards. Approach: The ISO 9126 on software product quality and ISO 12207 on software life cycle processes had been analysed to investigate the r...

2',3'-iso-Benzoabscisic acid (iso-PhABA), an excellent selective abscisic acid (ABA) analog, was developed in our previous work. In order to find its more structure-activity information, some structural modifications were completed in this paper, including the substitution of phenyl ring and replacing the ring with heterocycles. Thus, 16 novel analogs of iso-PhABA were synthesized and screened ...

Problem statement: The International Organization for Standardization (ISO) published a set of international standards related to the software engineering, such as ISO 12207 and ISO 9126. However, there is a set of cross-references between the two standards. Approach: The ISO 9126 on software product quality and ISO 12207 on software life cycle processes had been analyzed to invistigate the rel...

BACKGROUND Urinary 8-iso-PGF2α, a marker of oxidative stress, is influenced by the activation of NOX2. It is unclear if platelets 8-iso-PGF2α contribute to urinary 8-iso-PGF2α. METHODS AND RESULTS In a cross-sectional study, platelet, urinary, and serum 8-iso-PGF2α were determined in subjects with downregulation (X-linked chronic granulomatous disease [X-CGD], n=25) and upregulation (type II ...

Large organizations are faced with the problem of connecting equipment that not only represents a number of manufacturers, but a variety of disparate media, protocols, and interfaces as well. While these technologies are coexistent, their interconnectivity and communicability is desired in order to optimize use of these important corporate resources. In the short-run, one may run the transport ...

Context. While there is growing consensus on the existence of numerous dust-enshrouded red quasars, their discovery and detailed exploration is still an observational challenge. In the course of the near-mid-infrared AGN search combining the 6.7 μm ISOCAM Parallel Survey and 2MASS we have discovered 24 type-1 quasars about a third of which are too red to be discriminated by optical/UV search te...

Entropy generation of double diffusive natural convection in a three dimensional differentially heated enclosure has been performed numerically. Vertical walls of enclosure are heated differentially and remaining walls are adiabatic. The obtained results were presented via iso-concentration, iso-temperatures, velocity vector projection, particle trajectories, velocity profiles, iso-entropy, loc...