نتایج جستجو برای: tfp

تعداد نتایج: 1386  

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017
Mehrdad Ghashghaeinia Mauro Carlos Wesseling Elena Ramos Polina Petkova-Kirova Sabrina Waibel Elisabeth Lang Rosi Bissinger Kossai Alzoubi Baerbel Edelmann Zohreh Hosseinzadeh Peter Dreischer Azam Shahvaroughi-Farahani Ulrich Mrowietz Martin Köberle Lars Kaestner Ingolf Bernhardt Antonio Martínez-Ruiz Thomas Wieder Florian Lang

BACKGROUND AND PURPOSE The high potency antipsychotic drug trifluoperazine (10-[3-(4-methyl-1-piperazinyl)-propyl]-2-(trifluoromethyl)-(10)H-phenothiazine dihydrochloride; TFP) may either counteract or promote suicidal cell death or apoptosis. Similar to apoptosis, erythrocytes may enter eryptosis, characterized by phosphatidylserine exposure at the cell surface and cell shrinkage. Eryptosis ca...

2013
Meghan K. Murphy Daniel J. Huey Andrew J. Reimer Jerry C. Hu Kyriacos A. Athanasiou

The insufficient healing capacity of articular cartilage necessitates mechanically functional biologic tissue replacements. Using cells to form biomimetic cartilage implants is met with the challenges of cell scarcity and donor site morbidity, requiring expanded cells that possess the ability to generate robust neocartilage. To address this, this study assesses the effects of expansion medium s...

2016
Hongqiang Yang Tian Yuan Xiaobiao Zhang Suyan Li Thomas J. Straka Eric J. Jokela

State-owned forestry enterprises are important elements of the forestry economy in China. The operational efficiency of such enterprises depends on technological progress and other input factors. Total factor productivity (TFP) is an important means to evaluate the efficiency of technical elements. The growth of production efficiency can be classified into efficiency variation and technical var...

1999
Matthew Slaughter

The U.K. skill premium fell from the 1950s to the late 1970s and then rose very sharply. This paper examines the contributions to these relative wage movements of international trade and technical change. We first measure trade as changes in product prices and technical change as TFP growth. Then we relate price and TFP changes to a set of underlying factors. Among a number of results, we find ...

Journal: :J. Economic Theory 2013
Nicolas Petrosky-Nadeau

The financial crisis of 2008 was followed by sharp contractions in aggregate output and employment and an unusual increase in aggregate total factor productivity (TFP). This paper attempts to explain these facts by modeling the creation and destruction of jobs in the presence of heterogeneity in firm productivity and frictional credit and labor markets. The aggregate level of TFP is determined ...

2004
Paul Beaudry Franck Portier

Here we supplement some earlier work (Beaudry and Portier [2004]) with some new evidence obtained from Japanese and U.S. sectoral data. Our results show that (i) In the U.S. as well as for Japan, Stock Prices short run movements incorporate most (all) of the long run shocks to Total Factor Productivity and (ii) the Stock Price news is indeed a shock that does not affect sectoral TFP s on impact...

2015
Wei-Ming Wu

Rather than adding up all cost items of ship operation in the traditional vessel-based approach, this paper develops a theoretical model to evaluate and decompose the total factor productivity (TFP) growth of the container shipping industry in Taiwan. The results show that scale economies and ship size economies play the dominant roles in improving TFP growth. Since 2006, the dominance of TFP g...

Journal: :The Journal of biological chemistry 1986
R C Hunt L Marshall-Carlson

When human erythroleukemic (K562) cells were incubated with 25 microM trifluoperazine (TFP), a drug that inhibits both calmodulin-dependent and calcium-activated phospholipid-dependent kinases, the number of transferrin receptors detected on the cell surface was reduced to approximately half with no change in the affinity of the remaining surface receptors. Removal of the TFP from the incubatio...

2013
Fan Wu Andrea Kirmaier Robert Goeken Ilnour Ourmanov Laura Hall Jennifer S. Morgan Kenta Matsuda Alicia Buckler-White Keiko Tomioka Ronald Plishka Sonya Whitted Welkin Johnson Vanessa M. Hirsch

The antagonistic interaction with host restriction proteins is a major driver of evolutionary change for viruses. We previously reported that polymorphisms of the TRIM5α B30.2/SPRY domain impacted the level of SIVsmm viremia in rhesus macaques. Viremia in macaques homozygous for the non-restrictive TRIM5α allele TRIM5(Q) was significantly higher than in macaques expressing two restrictive TRIM5...

2003
M. T. SOBUS C. E. HOLMLUND N. F. WHITTAKER

Trifluperidol (TFP), at a concentration of 100 ,M, inhibited the 24-h growth of Saccharomyces cerevisiae by about 30%. Effects on lipid metabolism were investigated by monitoring the incorporation of [1-14C]sodium acetate into various lipid fractions after 4 and 24 h ofgrowth in the presence of several concentrations of TFP. Although little effect was noted on the amount of free sterols, 24-h i...

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