The author reviewed present status and progress of endocrine nuclear medicine including thyroid, parathyroid, adrenocortical, adrenomedullary and somatostatin receptor imaging and also radionuclide therapy of Basedow's disease, metastatic foci of post-operative thyroid cancer and malignant neural crest tumor. Relatively new imaging agents include 99mTc-MIBI and 99mTc-tetrofosmin for parathyroid...

c p p r p q m Rest and stress myocardial perfusion imaging, described nearly 4 decades ago (1), is now performed in 9 million people annually in the United States (2). The procedure provides clinically useful data regardless of whether the tracer is a monovalent cation such as potassium, thallium, or rubidium; a highly diffusible agent such as O-labeled water; an amino acid precursor such as am...

Myocardial perfusion scintigraphy (MPS) is the only widely available method of direct assessment of myocardial perfusion. It involves intravenous injection of small amounts of a radioactive tracer at peak stress, followed by imaging of the heart with a gamma camera. There are three commercially available tracers: thallium-201 and two technetium-labelled tracers, sestamibi and tetrofosmin. All t...

METHODS: Nineteen vials of tetrofosmin were radiolabelled with Tc and the percentages of the RCP were determined. Five different methods were compared with the standard RCP testing method (ITLC-SG, 2x20 cm): Whatman 3MM (1x10 cm) with acetone and dichloromethane (method 1); Whatman 3MM (1x10 cm) with ethyl acetate (method 2); aluminum oxide-coated plastic thin-layer chromatography (TLC) plate (...