Protein Disulfide Isomerase-Like protein of the Testis (PDILT) is a testis-specific member of the PDI family. PDILT displays similar domain architecture to PDIA1, the founding member of this protein family, but lacks catalytic cysteines needed for oxidoreduction reactions. This suggests special importance of chaperone activity of PDILT, but how it recognizes misfolded protein substrates is unkn...

We aimed to study the toxic effect of Monosodium Glutamate (MSG) on the morphology and the structure of the rat testis and to see if there is a potential recovery of the adverse effects of MSG. The study was performed on forty-eight young adult Wistar male rats (age 10 weeks). The animals were divided randomly into Control group (C) and Experimental group (E), each containing 24 rats. Each grou...

Recent work has demonstrated the existence of a subunit structure in chromatin. Hewish and Burgoyne have reported [I] that a large proportion of DNA in isolated rat liver nuclei is digested by an endogenous Ca++ and Mg+’ dependent endonuclease into fragments which are integral multiples of a unit length. Louie has found [2] that DNA from mouse liver nuclei or from the nucleoprotein complex of p...

Testicular torsion, a urological emergency, occurs due to absence of testicular blood supply secondary to a mechanical twist of the spermatic cord. The authors describe a 28-year-old male who presented with torsion symptoms, first in the left testicle and four months later in the right testicle. Doppler ultrasound and surgical exploration revealed disruption of blood flow but no evidence of spe...

Testis tortion in the newborn (especially antenatal testis tortion) is observed very rarely and constitutes 10-12% of childhood testis tortions. In testis tortion, firm and painless testicular tissue is palpated on physical examination. Doppler ultrasonography is a sensitive method in the diagnosis. In cases of neonatal testis tortion, the testis can be saved with appropriate surgical explorati...

A rete testis cannulation technique was used to compare the secretion of rete testis fluid with the production of spermatozoa and histological testicular parameters in Ile-de-France rams. Thirteen testes were cannulated and rete testis fluid variables were compared to histological variables of the same testis. The rate of flow of rete testis fluid was significantly (P less than or equal to 0.05...

INTRODUCTION Few oral antidiabetic drugs have been evaluated for their reproductive complication. This study aimed to evaluate the effect of metformin, pioglitazone and sitagliptin on the structure of male reproductive system through an immunohistopathological study. MATERIAL AND METHODS Sprague-Dawley male rats were injected with streptozotocin. The diabetic rats were divided into four group...

This study was conducted to assess the effect of melatonin on the structure of testis and spermatogenesis dynamics in neonate vitrified testis grafts. Neonate vitrified testes, candidates for transplantation heterotopically to experiment or control groups, were warmed in thawing media which had or did not have a supplement of 100 μM melatonin, respectively. Following transplantation, melatonin ...

This study aims to investigate effect of torsion on testicular stiffness alteration in affected and concomitant testis using improved ultrasound method of shear wave elastography (SWE). We compared the morphology of the testicular spermatogenesis assessed with Johansen's scale on histology specimens with a mean stiffness measured by SWE. A total of 18 New Zealand white male rabbits were divided...

Transverse testicular ectopia, an extremely rare anomaly, is a deviation of testicular descent resulting in unilateral location of both testes, usually associated with an inguinal hernia, with the spermatic cord of the ectopic testes originating from the appropriate side. In most reported cases, the correct diagnosis was not made preoperatively. But we made a diagnosis of transverse testicular ...