Solid tumours in the inguinal scrotal area (inguinal, testicular and para-testicular) are infrequent in the clinic. After its observation, depending on factors such as age, time of evolution, metastatic disease and blood markers at diagnosis, clinicians oriented to one origin or other. However, this approach may lead to a wrong diagnosis and treatment approach. In this publication, we report an...

Spontaneous neoplasms in 930 control Wistar rats from five carcinogenicity bioassays conducted between 1990 and 1995 were reviewed and compared with review findings in studies between 1980 and 1990. Mean survival at 104 weeks was 55% for males and 60% for females, similar to that of the previous review. A total of 1599 neoplasms was diagnosed in 361 (78%) male and 415 (89%) female rats; 1293 (8...

Ovarian-type surface epithelial neoplasms of the testis and paratestis are uncommon, and the mucinous subtype is particularly rare. These tumors represent a counterpart to ovarian cancer. Malignant tumors have the potential for metastatic spread and are often fatal. The case of a 59-year-old man with testicular mucinous adenocarcinoma is presented. Computed tomography indicated involvement of t...

The complete form of androgen insensitivity syndrome (testicular feminization) occurs in a 46,XY karyotype with a mutant X-linked recessive gene that is responsible for the androgen intracellular receptor [l]. An individual with androgen insensitivity syndrome is a male pseudohermaphrodite. Phenotypic characterizations include scanty or absent axillary and pubic hair, slight vulvar hair, a rudi...

SUMMARY The establishment of a regional testicular tumour study group is described with emphasis on the importance of a local facility for tumour marker measurements by a fully integrated laboratory.

BACKGROUND To report the cases of adenomatoid tumors seen at Hospital Universitario La Paz in the last 15 years. METHODS A clinical, pathological, and surgical study was conducted of males with testicular or paratesticular tumors with a histological report of adenomatoid tumor. RESULTS Among the nine cases studied, seven had paratesticular and two intratesticular adenomatoid tumors. Treatme...

INTRODUCTION Testicular tumors are a heterogeneous group of neoplasms exhibiting diverse histopathology and can be classified as seminomatous and non-seminomatous germ cell tumor types. Mixed germ cell tumors contain more than one germ cell component and various combinations have been reported. Here, we present a rare case of a mixed germ cell tumor composed of seminoma, choriocarcinoma and ter...

Carcinoma in situ (CIS) is the common precursor of histologically heterogeneous testicular germ cell tumors (TGCTs), which in recent decades have markedly increased and now are the most common malignancy of young men. Using genome-wide gene expression profiling, we identified >200 genes highly expressed in testicular CIS, including many never reported in testicular neoplasms. Expression was fur...

MUKADA, T., ANDOR, N. and SASANO, N. Tumor of the Testis: An Attempt of Histological Classification According to WHO Guide Line. Tohoku J. exp. Med., 1981, 134 (4), 367-373 Testicular tumor in Japan is one of the evil neoplasms which have increased in incidence rate in recent years. In order to provide the basic data for the clinicopathological and epidemiological studies on testicular tumors, ...

This study is concerned with the behavior after transplantation of eleven human testicular cancers heterografted to the hamster cheek pouch. It was undertaken in an effort to establish an adequate supply of uniform and predictable tumor cells upon which investigations could be made into the biology of testicular cancer. Several reports are available concerning the be havior after heterotranspla...