The objective of the present study was to identify sperm abnormalities in young male patients with juvenile dermatomyositis (JDM). In 2005, 18 male JDM patients, diagnosed according to the criteria of Bohan and Peter, were followed at the Pediatric Rheumatology Unit and Rheumatology Division, of our Institution. Of the 18 males, 11 were pre-pubertal and 7 were post-pubertal. Two of 7 post-puber...

Objective: In the present study, it was aimed to investigate differences between clinical and histopathological features of testicular seminomatous non-seminomatous germ cell tumors diagnosed in our center recent 10 years. Methods: All patients whom diagnosis tumor histologically confirmed January 2010 May 2020 were involved study. The medical records screened Hematoxylin-Eosin (H+E) stained sl...

Platelet-derived growth factors (PDGFs) are paracrine factors with roles in mesenchymal-epithelial interactions during normal and pathologic processes. Previously, PDGF and its receptor (PDGFR) have been shown to be present in perinatal, peripubertal, and adult rat testes. The role of PDGF in embryonic testicular cord formation is not known. The hypothesis tested is that PDGFs and PDGFRs are ex...

The present study was undertaken to investigate the protective effect of the filamentous cyanobacterium Spirulina platensis (S. platensis) on mercury (II) chloride (HgCl(2))-induced oxidative damages and histopathological alterations in the testis of Wistar albino rats. The animals were divided into four equal groups, i) control, ii) HgCl(2), iii) S. platensis and iv) combination of HgCl(2)+S. ...

Testicular weight and morphology, serum gonadotropins, intratesticular levels of testosterone and ABP levels in testicular interstitial fluid were studied in adult rats at intervals of 1 to 70 days after a single oral dose of 650 mg/kg methoxy acetic acid. At 3 days, this treatment resulted in the selective loss or depletion of pachytene and later spermatocytes from seminiferous tubules at all ...

BACKGROUND Testicular morphology and immunohistochemical studies have never been reported in genetically documented adult patients with 5 alpha-reductase type 2 deficiency (5α-R2 deficiency). CASE PRESENTATION We describe the testicular histopathology of a 17-year-old XY subject with 5α-R2 deficiency caused by the recurrent homozygous Gly115Asp loss of function mutation of the SRD5A2 gene.We ...

Six reproductive classes of male Oligosarcus hepsetus (Cuvier, 1829), a medium-sized carnivorous Characiform species, are described based on macroscopic and histological techniques. A total of 175 individuals were caught monthly between April 2001 and June 2002 in the Lajes Reservoir, Brazil, one of the largest impoundment areas in the state of Rio de Janeiro. The reproductive classes were base...

Drug-induced disturbances in reproductive hormones and gonadal morphology have been observed both in patients with epilepsy and in non-epileptic animals. Less is known about the influence of newer antiepileptic drugs including lamotrigine on reproduction. Lamotrigine is now increasingly used both in epilepsy and psychiatric disorders. Sixty-five Wistar rats were fed by gastric tube either 5 mg ...

OBJECTIVE To investigate a possible protective role of lycopene on adriamycin (ADR)-induced spermiotoxicity using quantitative, biochemical and histopathological approaches. DESIGN Experimental study. SETTING Firat University Medical School, Experimental Research Centre, Elazig, Turkey. ANIMALS Twenty four Sprague Dawley rats (8-weeks old) INTERVENTION(S) Adriamycin (10 mg kg(-1)) was i...

The testicular mesothelioma is one of the rare tumor from other types of mesotheliomas (less than 1%)[9, 43, 81, 104]. In light of this are clear of the difficulties encountered by some clinicians, radiologists, pathologists and cytologists in differential diagnosis. In addition, they are so rare that there is no more the researcher, which would focus in his hands a sufficient number of his own...