This study highlights the importance of parent-child communication of sensitive health-related issues, specifically the importance of cancer prevention discussions. For females, communication about breast cancer has been desensitized; yet, testicular cancer is not being discussed among males, even though it is highly curable when caught early. Testicular cancer primarily impacts males ages 15–4...

Objectives: The present study was conducted to evaluate the relationship between testicular volume measured by using Ultrasonography and seminogram to determine the testicular function in male infertility in Mysore, Karnataka, India. Materials and methods: A total of 274 infertile and 130 normozoospermic males were recruited for this study from Mysore, India. The testicular volumes of all subje...

Testicular biopsy was considered the cornerstone of male infertility diagnosis for many years in men with unexplained infertility and azoospermia. Recent guidelines for male infertility have limited the indications for a diagnostic testicular biopsy to the confirmation of obstructive azoospermia in men with normal size testes and normal reproductive hormones. Nowadays, testicular biopsies are m...

INTRODUCTION Testicular germ cell tumors are the most common malignancies in men. Testicular torsion is also a scrotal phenomenon seen in adolescence and adulthood. The co-occurrence of these two scrotal disorders is extremely rare. CASE PRESENTATION A 28-year-old East Asian man presented at our hospital with painless bilateral scrotal swelling. Both scrotal ultrasonography and computed tomog...

background: the metabolic syndrome (mes) is associated with a high risk of diabetes and cardiovascular disease. the aim of the present study was to determine the prevalence of the metabolic syndrome as well as cut-off points for waist circumference (wc) for diagnosis of mes in zahedan, southeast iran. methods: totally, 1802 people (735 men and 1067 women) with metabolic syndrome were surveyed a...

BACKGROUND The xenografting of pre-pubertal human testicular tissue to an immunodeficient mouse is a theoretical strategy for restoring fertility in childhood cancer patients, while circumventing the risk of malignant recurrence. This study aimed at comparing the grafting of pre-pubertal and adult murine testicular tissue, as well as that of human adult testicular tissue, to two immunodeficient...

Objective To investigate effects of cryopreservation on changes of the ultrastructure of human testicular sperm and evaluate the efficacy of cryopreserving testicular tissue as a source of sperm for assisted reproduction. Methods Testicular biopsy tissues were obtained from infertile patients (n=12) with obstructive azoospermia and cryopreserved. Testicular sperm motility was observed after in ...

testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in europe and north america. one suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. endocrine disrupting chemicals (edcs) have been a ma...

Testicular torsion is a well known urological emergency most common in the paediatric population. However, testicular can be complete, partial or intermittent. Intermittent rare adults and difficult to diagnose. We present case on intermittent 35 year old man that was initially misdiagnosed but later diagnosed by Spectral Doppler ultrasound.

Polycyclic aromatic hydrocarbons (PAHs), like benzo[a]pyrene (BaP), are ubiquitous environmental pollutants formed by the incomplete combustion of organic materials. The tripeptide glutathione (GSH) is a major antioxidant and is important in detoxification of PAH metabolites. Mice null for the modifier subunit of glutamate cysteine ligase (Gclm), the rate-limiting enzyme in GSH synthesis, have ...