Three Sus scrofa Piwi genes (Piwil1, Piwil2 and Piwil4) encoding proteins of 861, 985 and 853 aminoacids, respectively, were cloned and sequenced. Alignment of the Piwi proteins showed the high identity between Sus scrofa and Homo sapiens. Relative transcript abundance of porcine Piwil1, Piwil2 and Piwil4 genes in testes, ovaries and oocytes derived from sexually immature and mature animals was...

Cadmium (Cd) is associated with male infertility and poor semen quality in humans. Increasing evidence demonstrates that Cd induces testicular germ cell apoptosis in rodent animals. However, the molecular mechanisms of Cd-induced testicular germ cell apoptosis remain poorly understood. In the present study, we investigated the role of endoplasmic reticulum (ER) stress on Cd-evoked germ cell apo...

OBJECTIVES Testicular cancer is the most prevalent malignant neoplasm in young men. The key problem in screening for malignant testicular tumors and their main risk factors (undescended testes and testes which descended only after medical treatment) is to reach the target group of "young men". MATERIALS AND METHODS In five different military medical centers of German Armed Forces, 1600 young ...

The treatment of undescended testes in infancy and childhood, and the timing of treatment have been reviewed recently by Johnston (1965) and by the Brit. med. J. (1965). From a practical point of view, it is important to know, (1) the incidence of undescended testes in the newbom, and (2) the spontaneous alterations in position of the testes during infancy and childhood. With regard to the firs...

Here we introduce multivariate tensor-based surface morphometry using holomorphic one-forms to study brain anatomy. We computed new statistics from the Riemannian metric tensors that retain the full information in the deformation tensor fields. We introduce two different holomorphic one-forms that induce different surface conformal parameterizations. We applied this framework to 3D MRI data to ...

HE development of the testes and associated organs in Drosophiln melanoT g m t m has been studied by many investigators (STERN 1940. 1941a. b; STERN and HADORS 1939; URSPRUNC 1963). A review of the literature has been given by RODI:.NSTIXN (1950). During the larval and early pupal stages. the testes are ellipsoidal in form. Following attachment of the testes to the developing seminal vesicles. ...

We extended a generic whole-body physiologically based pharmacokinetic (PBPK) model for rats and humans for organs of the reproductive and endocrine systems (i.e., the testes and the thyroid gland). An extensive literature search was performed, first, to determine the most generic organ model structures for testes and thyroid across species, and, second, to identify the corresponding anatomic a...

Information regarding the domestic cat as a model animal in biomedical research has not been widely carried out. This study was aimed to see correlation between testicular weight, volume and total sperm count left testicle, right testicle both testes. In addition, this examine effect of weight on quantitative histomorphometry testes cats Indonesia. The results showed that there no difference Te...

Renal interstitial fibrosis (IF) is an important pathologic manifestation of disease progression in a variety of chronic kidney diseases (CKD). However, the quantitative and reproducible analysis of IF remains a challenge, especially in experimental animal models of progressive IF. In this study, we compare traditional polarized Sirius Red morphometry (SRM) to novel Second Harmonic Generation (...

Retractile testes [1] Prepubertal boys can have an exaggerated cremasteric reflex. The testis may retract out of the scrotum in the cold, on examination, on excitement or on physical activity. It is normal and will descend when relaxed and warm, or it can be manipulated back into the scrotum. Retractile testes do not need any treatment but do need close follow-up until puberty, as they can beco...