In the long-term management of ulcerative colitis patients, repeat dosing maybe required. Since 5-ASA is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. The aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-ASA deliver...

The International Journal of Integrated Care (IJIC) is an online, open-access, peer-reviewed scientific journal that publishes original articles in the field integrated care on a continuous basis.IJIC has Impact Factor 5.120 (2020 JCR, received June 2021)

objective: to evaluate the effect of meperidine, commonly administered for labor analgesia, on newborn weight and peripartum breastfeeding during two months after delivery. materials and methods: this pilot cohort study was conducted between october 2010 and october 2011 at the women hospital of the tehran university of medical sciences. in this study, we examined the effects of meperidine on b...

We obtained data recorded in the Danish medical birth registry on all women with a prolonged pregnancy in the first delivery and in a subsequent delivery, during 1980-94, and a 5% sample of all women with two or more pregnancies recorded in the period 1980-92 (only the first two deliveries were used for analysis). The information on gestational age in the registry was obtained from birth record...

delivery of exogenous materials such as nucleic acids, peptides, proteins, and drugs into cells is an important strategy in modern cellular and molecular biology. recently, the development of gene carriers for efficient gene transfer into cells has attracted a great attention. furthermore, lack of effective drug delivery is one of the major problems of cancer chemotherapy. many physical methods...