نتایج جستجو برای: terazosin hcl

تعداد نتایج: 11695  

2002
M. L. Morton L. J. Butler T. A. Stephenson Melita L. Morton Laurie J. Butler Thomas A. Stephenson Fei Qi

The primary photodissociation dynamics of allyl chloride upon excitation at 193 nm is investigated in a crossed laser-molecular beam scattering apparatus. Tunable vacuum ultraviolet ~VUV! photoionization of the products provides a unique ability to learn about the secondary reaction products of the nascent photoproducts formed. The data show evidence for four significant primary reaction channe...

Journal: :Blood 2015
Sascha Dietrich Jennifer Hüllein Stanley Chun-Wei Lee Barbara Hutter David Gonzalez Sandrine Jayne Martin J S Dyer Małgorzata Oleś Monica Else Xiyang Liu Mikołaj Słabicki Bian Wu Xavier Troussard Jan Dürig Mindaugas Andrulis Claire Dearden Christof von Kalle Martin Granzow Anna Jauch Stefan Fröhling Wolfgang Huber Manja Meggendorfer Torsten Haferlach Anthony D Ho Daniela Richter Benedikt Brors Hanno Glimm Estella Matutes Omar Abdel Wahab Thorsten Zenz

Hairy cell leukemia (HCL) is marked by near 100% mutational frequency of BRAFV600E mutations. Recurrent cooperating genetic events that may contribute to HCL pathogenesis or affect the clinical course of HCL are currently not described. Therefore, we performed whole exome sequencing to explore the mutational landscape of purine analog refractory HCL. In addition to the disease-defining BRAFV600...

Journal: :Journal of Korean Society for Clinical Pharmacology and Therapeutics 2001

Journal: :Haematologica 2005
Hang Quach Henry Januszewicz David Westerman

Hairy cell leukemia variant (HCL-v) is a rare form of a chronic B-cell lymphoproliferative disorder. Unlike typical hairy cell leukemia (HCL) where the complete response (CR) rate to 2-chlorodeoxyadenosine and 2'-deoxycoformycin can approach about 90%, in HCL-v CR is rare and partial response (PR) occurs in approximately 50% with these agents. Rituximab treatment in relapsed or refractory HCL r...

Journal: :Pakistan journal of pharmaceutical sciences 2014
Nuran Gundogdu Meltem Cetin

In this study, the preparation and in vitro characterisation of metformin HCl-loaded CS-PLGA nanoparticles (NPs) were aimed. The prepared nanoparticles (blank nanoparticles (C-1), 50 mg of metformin HCl loaded nanoparticles (C-2) and 75 mg of metformin HCl loaded nanoparticles (C-3) ranged in size from 506.67±13.61 to 516.33±16.85 nm and had surface charges of 22.57±1.21 to 32.37±0.57 mV. Low e...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2011

2014

This study was performed to clarify the effects of lidiocaine Hcl, ketamine Hcl and their combination injected into the sacrococcygeal space for posterior epidural analgesia in buffaloes. Five adult buffaloes were randomly received 3 treatments with 2 week interval. The treatments were 7.5 ml of lidiocaine Hcl 2% (Group I), 7.5 ml of ketamine Hcl 2% (Group II) and 7.5 ml combination of lidiocai...

2015
Sang-Yong Shin Seung-Tae Lee Hee-Jin Kim Chang-Seok Ki Chul Won Jung Jong-Won Kim Sun-Hee Kim

Dear Editor, Differentiation of classic hairy cell leukemia (HCL-c) from HCLvariant (HCL-v) or splenic marginal zone lymphoma (SMZL) is important owing to their different treatment strategies and prognostic implications. Recently, testing for BRAF V600E mutations was suggested as an important diagnostic option for HCL-considering that it was exclusively detected in almost all cases [1]. The BRA...

2014
Nicola J. Weston-Bell Francesco Forconi Hanneke C. Kluin-Nelemans Surinder S. Sahota

A functional B-cell receptor (BCR) is critical for survival of normal B-cells, but whether it plays a comparable role in B-cell malignancy is as yet not fully delineated. Typical Hairy Cell Leukemia (HCL) is a rare B-cell tumor, and unique in expressing multiple surface immunoglobulin (sIg) isotypes on individual tumor cells (mult-HCL), to raise questions as to their functional relevance. Typic...

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