BACKGROUND Down syndrome is associated with various forms of thyroid dysfunction, hypothyroidism being the most common. The additive effects of both co-morbid conditions lead to further amplification of the clinical problems in these children with Down syndrome. OBJECTIVE The purpose of this prospective study was to know the prevalence of thyroid dysfunction in Down Syndrome children below th...

OBJECTIVES To investigate the causes of congenital hypothyroidism in children more than 3 years of age and to document the frequency of transient vs permanent hypothyroidism. DESIGN Hospital based observational study. SETTING Pediatric endocrine clinic of a medical college. PATIENTS Children over 3 years of age, on treatment for congenital hypothyroidism. INTERVENTION Thyroid function t...

BACKGROUND The impact of subclinical hypothyroidism on the cardiovascular risk is still debated. We aimed to measure the relationship between subclinical hypothyroidism and the left atrial (LA) pressure. METHODS The LA pressures and thyroid function were measured in consecutive patients undergoing atrial fibrillation (AF) ablation, who did not have any known heart failure, structural heart di...

OBJECTIVE The objective of this study was to evaluate the incidence of hypothyroidism with adjuvant treatment in oral tongue carcinoma patients treated primarily with surgery. MATERIALS AND METHODS A retrospective review was carried out to analyze hypothyroidism incidence and its relation to adjuvant treatment (radiation/radio-chemotherapy) in oral tongue carcinoma after the primary surgical ...

Congenital hypothyroidism occurs in approximately 1 in 2000 newborns and can have devastating neurodevelopmental consequences if not detected and treated promptly. While newborn screening has virtually eradicated intellectual disability due to severe congenital hypothyroidism in the developed world, more stringent screening strategies have resulted in increased detection of mild congenital hypo...

Tyrosine kinase inhibitors are relatively new targeted therapy drugs used for the treatment of metastatic clear cell kidney carcinoma, gastrointestinal stromal tumours, thyroid carcinoma and pancreatic neuroendocrine tumours during the progression of the disease. Hypothyroidism or thyroid dysfunction is often a side effect of this treatment. Therefore, monitoring of thyroid hormone levels bef...

results Right atrial NOS activity decreased with aging and hypothyroidism. Cav-1 expression increased with aging and hypothyroidism. Conversely, left ventricular NOS activity increased with aging and hypothyroidism while the expression of both caveolin isoforms decreased in adult and hypothyroid groups. In the renal medulla, hypothyroidism reduced NOS activity in young and raised it in adult an...

Aim: The aim of the study was to determine whether certain cognitive domains exist in assessment functions HD patients, patients with hypothyroidism and concomitant hypothyroidism.
 Material methods: were divided into 3 groups according nosology: Group I – 21 hypertensive disease (HD); II 18 hypothyroidism, III 19 Results: It revealed that had a decrease memory test proposed by A.R. Luria ...

Hyponatremia has been reported in the elderly with hypothyroidism and myxedema, but this has not been a universal finding in clinical studies and there have been only a few reports in children. We report a case of an infant who developed hyponatremia due to severe primary hypothyroidism. A 4-month-old ex-preterm male, who had been euthyroid on the newborn screen, developed unexplained hospital-...