Prolactin has different functions, including cytokine secretion and inhibition of the suppressor effect of regulatory T (Treg) cells in healthy individuals. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by defects in the functions of B, T, and Treg cells. Prolactin plays an important role in the physiopathology of SLE. Our objective was to establish the participation...

An electron spectrometer was used to measure the and ion spectra in two different irradiations of implosion laser deuterated spherical shell targets at direct fast ignition experiments on Gekko-LFEX facility. In transverse irradiation against LFEX axis, low effective hot temperature (Teff) huge neutron yield (Ny) could be obtained although high Teff Ny observed axial irradiation. irradiation, e...

This study was aimed to analyze teff (Eragrostis tef) market chain in south west Shoa zone with objective of factors affecting supply using two stage ordinary least square approaches. The majority Ethiopia’s population earns its livelihood primarily from agriculture. Cereals is the first Ethiopia area coverage and production. Teff a major staple food crop Ethiopia. Both primary secondary data w...

ABSTRACT. Teff [Eragrostis tef (Zuccagni) Trotter] is cereal grain native to Ethiopia as staple food millions of people. However, no research work has been reported for characterization with respect water-soluble total sugars and free amino acids in white brown teff grains. The main objective this study was determine (TFAA) the varieties. determined sugar contents sample extract ranged between ...

We explore the application of artificial neural networks (ANNs) for the estimation of atmospheric parameters (Teff , log g , and [Fe/H]) for Galactic Fand G-type stars. The ANNs are fed with medium-resolution (∆λ ∼ 1 − 2 Å ) non flux-calibrated spectroscopic observations. From a sample of 279 stars with previous high-resolution determinations of metallicity, and a set of (external) estimates of...

ABSTRACT. In this study, the level of selected heavy metals in cement dust, soil and teff samples collected from around Mugher Habesha factories, Ethiopia were determined using flame atomic absorption spectroscopy (FAAS). The digested properly optimized acid digestion a mixture 5 mL HNO3:1 H2SO4:1 HClO4 at 200 oC for 2 h dust; 3 HNO3:4 HClO4:1 H2O2 300 °C HNO3:3 1:30 samples. mean concentration...

The cyclic AMP/protein kinase A (cAMP/PKA) pathway is one of the most common and versatile signal pathways in eukaryotic cells. A-kinase anchoring proteins (AKAPs) target PKA to specific substrates and distinct subcellular compartments providing spatial and temporal specificity for mediation of biological effects channeled through the cAMP/PKA pathway. In the immune system, cAMP is a potent neg...

UNLABELLED Cell-based therapy has potential therapeutic value in autoimmune diseases such as rheumatoid arthritis (RA). In RA, reduction of disease activity has been associated with improvement in the function of regulatory T cells (Treg) and attenuated responses of proinflammatory effector T cells (Teff). Mesenchymal stem cells (MSCs) and related multipotent adult progenitor cells (MAPC) have ...

Several animal autoimmune disorders are suppressed by treatment with the GM1 cross-linking units of certain toxins such as B subunit of cholera toxin (CtxB). Due to the recent observation of GM1 being a binding partner for the endogenous lectin galectin-1 (Gal-1), which is known to ameliorate symptoms in certain animal models of autoimmune disorders, we tested the hypothesis that an operative G...