PURPOSE To compare dry eye signs and symptoms between patients with preoperative low and normal Schirmer test after Photorefractive keratectomy (PRK). METHODS In this prospective, nonrandomized, comparative case series, 76 eyes of 76 patients were preoperatively categorized into two groups according to selected criteria for characterization of tear film status: the low Schirmer test value (ST...

The hydrophobic surfactant proteins B (SP-B) and C (SP-C) are tightly bound to phospholipids. These proteins play important roles in maintaining the surface tension-lowering properties of pulmonary surfactant. Surfactant protein A (SP-A) and D (SP-D) are extremely hydrophilic and are thought to have a role in recycling surfactant and especially in improving host defense in the lung. Moreover, S...

We compared the relative value of the tear film breakup time, Schirmer test, lactoferrin immunologic assay and rose bengal staining in 156 patients with varying severity of symptoms characteristic of keratoconjunctivitis sicca and in 39 controls. Statistical analysis showed that in patients with minimal ocular irritation the Schirmer test in combination with the lactoferrin immunologic assay pr...

PURPOSE To develop a controlled-environment chamber (CEC) for mice and verify the effects of a low-humidity setting on ocular surface signs in normal mice. METHODS Eight- to 12-week-old BALB/c mice were used in a controlled-environment chamber (CEC) where relative humidity (RH), temperature (T), and airflow (AF) are regulated and monitored. Mice were placed into the CEC and exposed to specifi...

Hypertension is a chronic medical condition in which blood pressure the arteries elevated. This research work studied effect of antihypertensive drugs specifically beta adrenergic blockers (atenolol) and angiotensin converting enzymes (lisinopril) on tears secretion stability adults. A total 75 people (35 65years) male female participated completed study with mean age 52.8±1.83years. These subj...

The dry eye syndrome is a common eye symptom causing blurry vision. To meet the demand of the modem world students and professionals are compelled to expose themselves to the computer screen for long stretch of time, which is one of the causes of dry eye. It is not always feasible to instil eyes with artificial tears time to time to protect them from dryness. Rather to adopt any simple physiolo...

PURPOSE To investigate the differentiation of conjunctival epithelium and tear film function in pingueculae. METHODS Twelve patients (12 eyes) who underwent simple excision for pingueculae were enrolled in the study. Immunostaining for K14, K19, K10, MUC5AC, Pax6, P63, Ki67, and K16 was performed on the pinguecula epithelium and normal conjunctival epithelium. Schirmer I test results and tear...

A 3-year-old child, his mother, and his uncle were found to have asymptomatic distichiasis accompanied by corneal hypoaesthesia. Slit-lamp examination of the mother and her brother revealed normal corneas, but bilateral punctate epithelial staining was found in the child. In addition the child suffered from corneal erosion in his left eye due to decreased tear secretion after left occipital cra...

Purpose: The established methods for observing the morghnl-og;i nF the teer film a=~ based on ;nierfrrenc~ techniques. Since interference patterns are visible only in e pathologically thickened tear film, these techniques are not useful for the physiological tear film morphology. Methods: A ne;.approach is Brewster Angle Microscopy n-which allows the studv of ultra-thin films. In ophthalmology ...