BACKGROUND The widespread use of antiretroviral therapies has led to considerable concerns about the prevalence of drug-resistant, as transmission of drug-resistant (TDR) strains poses a challenge for the control of the HIV-1 epidemic. METHODS We conducted an epidemiological study enrolling treatment-naïve HIV-1-positive subjects at the Peking Union Medical College Hospital since 1991. Drug r...

Abstract Nitrates when found in excess in the groundwater, is a health hazard. Nitrates can easily be transported by groundwater movement and may eventually reach aquifers located far away from the contamination location. It is important to monitor the nitrate movement in the groundwater to predict the extent of nitrate contamination. Traditionally, nitrate movement is monitored by sampling gro...

The origin and function of the increased of "atypical lymphocytes" which appear in the blood of patients with many inflammatory diseases is not known. Leukocyte suspensions from eight patients with systemic lupus erythematosus (SLE), five patients with other rheumatic diseases, and five patients with infectious diseases were pulse-labeled with tritiated thymidine (Tdr-(3)H) and sampled after 5 ...

BACKGROUND Transmitted drug resistance (TDR) is critical to managing HIV-1-infected individuals and being a public health concern. We report on TDR prevalence and include analyses of phylogenetic clustering of HIV-1 in a predominantly men who have sex with men cohort diagnosed during acute/recent HIV-1 infection in New York City. METHODS Genotypic resistance testing was conducted on plasma sa...

Human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) is an important public health issue. In Brazil, low to intermediate resistance levels have been described. We assessed 225 HIV-1 infected, antiretroviral naïve individuals, from HIV Reference Centers at two major metropolitan areas of Sao Paulo (Sao Paulo and Campinas), the state that concentrates most of the Brazilia...

This paper presents a model-based approach to determine dielectric constants from time domain reflectometry TDR measurement in highly conductive soils. It makes use of information contained in the TDR signal from the reflection at the surface of the soil rather than the reflection from the end of the probe. The TDR method is widely used to determine the volumetric water content of soils. Common...

During 2007-2008, surveillance of transmitted human immunodeficiency virus (HIV) drug resistance (TDR) was performed following World Health Organization guidance among clients with newly diagnosed HIV infection attending voluntary counseling and testing (VCT) sites in Ho Chi Minh City (HCMC), Vietnam. Moderate (5%-15%) TDR to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) was observed ...

Based on the principle of time domain reflectometry(TDR) cable length measurement, the principle error of the TDR cable length measurement is analyzed. Methods for reducing cable length measurement error are analyzed. Two cable length measurement systems based on the TDR principle are designed. The high-precision time interval measurement module is the core of the first measurement system. The ...

Test-driven reuse (TDR) proposes to find reusable source code through the provision of test cases describing the functionality of interest to a developer. Proponents claim that their TDR approaches work well. This paper presents the results of an experiment to evaluate the ability of state-of-the-art TDR tools to locate reusable source code for realistic tasks. We find that non-trivial function...

Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it...