The relative importance of antithrombin and anti-factor Xa activities of heparin fractions required to achieve optimal antithrombotic effects is unknown. To study this, we measured the effects of standard heparin, an octasaccharide heparin fraction (anti-factor Xa activity only), and dermatan sulfate (antithrombin activity only) on the prevention of thrombosis and related this to their anticoag...

BACKGROUND AND AIMS Obesity and impairments in metabolic health are associated with reductions in exercise capacity. Both whey protein isolates (WPIs) and vitamin E tocotrienols (TCTs) exert favorable effects on obesity-related metabolic parameters. This research sought to determine whether these supplements improved exercise capacity and increased glucose tolerance in diet-induced obese rats. ...

 Targeted cancer therapies (TCT) are drugs that specifically act on molecular targets within the cancer cell causing its regression and/or death. Although TCT showed clinically important gains in survival within the indications that did not see any improvements in past, they also came at considerable cost.  Different policies in drugs’ pricing and reimbursement among European countries that w...

BACKGROUND Attenuation correction of a single photon emission computed tomography (SPECT) image is possible using computed tomography (CT)-based attenuation maps with hybrid SPECT/CT. CT attenuation maps acquired during breath holding can be misaligned with SPECT, generating artifacts in the reconstructed images. The purpose of this study was to investigate the effects of respiratory phase duri...

BACKGROUND Staphylococcus aureus is one of the most important contagious bacteria causing subclinical bovine mastitis. This bacterial infection is commonly identified by determine the pathogen in bovine milk samples through conventional technique including coagulase test. However, this test has several disadvantages as low sensitivity, risk of biohazard, cost expensive, and limited preparation ...

A new recessive mutation affecting tail length is described. It is unlinked to the Tlt-complex on chromosome 17 and yet it shows cumulative phenotypic effects with several t-complex mutations: T, TCu, tct and Fu". It does not interact with five different nonchromosome I7 mutations that affect tail length. Thus, t-int is a tail modifier with surprisingly specific interactions. HE proximal part o...

BACKGROUND The identification and characterization of antigens expressed in Trypanosoma cruzi stages that parasitize mammals are essential steps for the development of new vaccines and diagnostics. Genes that are preferentially expressed in trypomastigotes may be involved in key processes that define the biology of trypomastigotes, like cell invasion and immune system evasion. METHODOLOGY/PRI...

Dynamic reconfiguration, the monitoring of power production, and fault diagnosis photovoltaic arrays, among other applications, require fast accurate models arrays. In literature, some use Lambert-W function to represent each module array, which increases calculation time. Other that implicit equations avoid do not inflection voltages simplify system nonlinear increasing computational burden. T...

In this work we investigated a method to determine time walk in an active silicon pixel sensor prototype using Edge-TCT with infrared laser charge injection. Samples were before and after neutron irradiation 5e14 neq/cm2. Threshold, noise calibration of the analogue front end determined external A spatially sensitive measurement collected was carried out Edge-TCT, showing uniform collection out...

We explore here surprising links between the time-cost-tradeoff problem and the minimum cost flow problem that lead to faster, strongly polynomial, algorithms for both problems. One of the main results is a new algorithm for the unit capacity min cost flow that culminates decades of efforts to match the complexity of the fastest strongly polynomial algorithm known for the assignment problem. Th...