Maintaining a proper balance between excitation and inhibition is essential for the functioning of neuronal networks. However, little is known about the mechanisms through which excitatory activity can affect inhibitory synapse plasticity. Here we used tagged gephyrin, one of the main scaffolding proteins of the postsynaptic density at GABAergic synapses, to monitor the activity-dependent adapt...

background: the piwi-interacting rna (pirna) pathway has an essential role in transposon silencing, meiosis progression, spermatogenesis, and germline maintenance. hiwi genes are critical for pirna biogenesis and function. therefore, polymorphisms in hiwi genes contribute to spermatogenesis defects and can be considered as risk factors for male infertility. the aim of the present study was to i...

Let BC be the model of behaviourally correct function learning as introduced by BB arzdins 4] and Case and Smith 8]. We introduce a mind change hierarchy for BC, counting the number of extensional differences in the hypotheses of a learner. We compare the resulting models BCn to models from the literature and discuss conndence, team learning , and nitely defective hypotheses. Among other things...

The beta(1)-adrenergic receptor (beta(1)AR) has one predicted site of N-linked glycosylation on its extracellular amino-terminus, but the glycosylation and potential functional importance of this site have not yet been examined. We show here that the beta(1)AR is glycosylated in various cell types and that mutation of the single predicted site of N-linked glycosylation (N15A) results in the for...

Two new cloned human cDNAs encode paralogs of the 85-kDa cytosolic phospholipase A2 (cPLA2). We propose to call these cPLA2beta (114 kDa) and cPLA2gamma (61 kDa), giving the name cPLA2alpha to the well known 85-kDa enzyme. cPLA2beta mRNA is expressed more highly in cerebellum and pancreas and cPLA2gamma more highly in cardiac and skeletal muscle. Sequence-tagged site mapping places cPLA2beta on...

The rapid expansion of the use of passive acoustic telemetry technologies has facilitated unprecedented opportunities for studying the behavior of marine organisms in their natural environment. This technological advance would greatly benefit from the parallel development of dedicated methodologies accounting for the variety of timescales involved in the remote detection of tagged animals relat...

This study deals with the transport behavior of the coarse-sediment at Masudagawa flood mitigation dam (FMD), Japan. Radio frequency identification system (RFID) was used to trace the displacement of the IC tagged particles following major flood events since June 2011. Through this, the relationship between recovery rate of the tagged particles and distribution of shear stress over the FMD bed ...

This study was conducted to test for the effect of three stinging behaviors QTLs (sting-1, sting-2 and sting-3) on the expression of guarding and stinging behavior of individual honey bees, and to determine if results of defensive behavior QTLs found in studies with Africanized honey bees could be extended to other populations of bees. Samples of guards, stingers, foragers and nurse bees were t...

We develop new methods for investigating problems of zero-sum type in general finite groups. We establish a new bound on Davenport’s constant for abelian groups that assymptotically improves the previously known bounds. We use tools from Representation Theory to study properties of zero-sum sequences through nilpotent ideals of group algebras. A new relationship between zero-sum problems and mu...

We present the exact solution of the asymptotics of the multiple packing problem in a finite space with a sum-type metric. 1 Consider the space Q of n−tuples over a finite set Q = [q] = {1, 2, . . . , q} (by standard convention in Combinatorics) and a sum-type metric d(x, y) = ∑n i=1 d(xi, yi), x = (x1, . . . , xn), y = (y1, . . . , xn). Let Bn(x, r) := {y ∈ Q : d(x, y) ≤ r} be the ball of radi...