The expense and complications in new drug entities have increased since last 3 decades, with concomitant recognition of the therapeutic advantages of controlled drug delivery. So focus has been given on development of sustained or controlled release drug delivery systems. Bilayer tablet is new novel of tablet for the successful development of controlled release formulation along with various fe...

The bioavailability of ciprofloxacin after its administration through a nasogastric (NG) feeding tube was studied in six healthy volunteers. Each subject received, on separate occasions, an intact 750-mg ciprofloxacin tablet, a crushed tablet as a suspension through an NG tube, and a crushed tablet as a suspension through an NG tube while receiving enteral feeding. No statistically significant ...

Clopidogrel bisulphate (anti-coagulant drug) is an enantio-selective chrial drug and needs to be monitored for the active form in tablet formulation. Hence, a stable tablet formulation was developed for clopidogrel using two different disintegrants of LHPC (to match as closely as possible to innovator tablet) and PVPP XL. Tablets were evaluated for stability analysis using validated analytical ...

The purpose of the present work was to prepare buccal adhesive tablets of miconazole nitrate. The simplex centroid experimental design was used to arrive at optimum ratio of carbopol 934P, hydroxypropylmethylcellulose K4M and polyvinylpyrollidone, which will provide desired drug release and mucoadhesion. Swelling index, mucoadhesive strength and in vitro drug release of the prepared tablet was ...

This experiment tested the influence of the lubricant magnesium stearate on the effectiveness of the drug acetaminophen in a mixture of glidants and excipients. There are many factors that can cause variation in the effectiveness of drugs in tablet form. Chief among them are the lubrication and glidant percentages, shear rate, tablet hardness and hydrophobicity. In order to allow the powder to ...

Tablet PCs are a new generation of notebook computers which provide multimodal input options of pen, voice and keyboard. Recently, these portable and flexible Tablet PCs have attracted attention as a potential tool in academic environments. This paper reviews the current use of Tablet PCs in teaching computer science and software engineering courses, presenting lectures and papers, and creating...

The posaconazole tablet formulation was developed to have improved bioavailability compared to the oral suspension. Here, we compared posaconazole plasma concentration (PPC) with the posaconazole oral suspension versus the tablet in Korean patients undergoing remission induction chemotherapy for hematologic malignancies. PPC was measured at 3, 8, and 15 days of treatment with the oral suspensio...

10.2217/14750708.2.3.349 © 2 part of The introduction of the 5-HT1B/1D agonist sumatriptan in 1991 marked a significant advance in the management of migraine. Sumatriptan was the first migraine pharmacotherapy designed to selectively target the neurovascular origin of migraine pain. Sumatriptan was introduced in several formulations – injection, nasal spray, conventional tablet or suppository. ...

Interaction through handheld devices is increasingly being used in virtual environments (VEs) for science, engineering, and entertainment applications. Some of the uniqueness of these nontraditional multiplatform user interfaces (MPUI) lies in the division of information between multiple displays and the remote control of information (e.g., using on computer to control a remote display). We per...

BACKGROUND The tablet formulation of ritonavir-boosted lopinavir (LPV/r; Kaletra) has many advantages over the soft gel capsule (SGC) formulation, including lower pill count, no refrigeration requirement, and no dietary restrictions. These advantages may help improve patient compliance and therefore increase adherence to treatment. However, there are limited data regarding patient preferences a...