Type II toxin-antitoxin (TA) systems are believed to be widely distributed amongst bacteria although their biological functions are not clear. We have identified eight candidate TA systems in the genome of the human pathogen Burkholderia pseudomallei. Five of these were located in genome islands. Of the candidate toxins, BPSL0175 (RelE1) or BPSS1060 (RelE2) caused growth to cease when expressed...

Bacterial abortive infection (Abi) systems are 'altruistic' cell death systems that are activated by phage infection and limit viral replication, thereby providing protection to the bacterial population. Here, we have used a novel approach of screening Abi systems as a tool to identify and characterize toxin-antitoxin (TA)-acting Abi systems. We show that AbiE systems are encoded by bicistronic...

Many toxin-antitoxin (TA) loci are known to strongly repress their own transcription. This auto-inhibition is often called 'conditional cooperativity' as it relies on cooperative binding of TA complexes to operator DNA that occurs only when toxins are in a proper stoichiometric relationship with antitoxins. There has recently been an explosion of interest in TA systems due to their role in bact...

Vehicle tailpipe emissions are major sources of air pollution and greenhouse gases. In addition to the ongoing efforts on emissions reduction, we believe there is a need to explore an innovating approach in which drivers routing decisions are influenced to minimize emissions and fuel consumption. In order to evaluate such transportation systems, we develop environmental traffic assignment model...

TADB2.0 (http://bioinfo-mml.sjtu.edu.cn/TADB2/) is an updated database that provides comprehensive information about bacterial type II toxin-antitoxin (TA) loci. Compared with the previous version, the database refined and the new data schema is employed. With the aid of text mining and manual curation, it recorded 6193 type II TA loci in 870 replicons of bacteria and archaea, including 105 exp...

Service robotics has increasingly become the focus of reflective research on new technologies over the last decade. The current state of technology is characterized by prototypical robot systems developed for specific application scenarios outside factories. This has enabled context-based Science and Technology Studies and technology assessments of service robotic systems. This contribution des...

Molecular dynamics simulations with a semiempirical interatomic potential predict the existence of a thermodynamically stable colloidal structure with nanometer-size Ta particles suspended in liquid Cu. The thermodynamic stability of this structure against coarsening, coalescence or transformation to a homogeneous solution is explained by a negative and strongly curvature-dependent tension of t...

山麦冬属( Li r io p e Lour .)植物系百合科植物 , 中国分布有 8 种(变种) 1 ] ,分别为山麦冬( Li r io p e s p ica ta Lour .) 、湖 北 山 麦 冬 ( Li r io pe sp icata Lour . var . prol i f e ra Y . T . Ma) 、短葶山麦冬 [ Li r io p e musacar li (Decne .) Bailey] 、阔叶山麦冬 ( Li r io p e p lat y phy l la Wang et Tang) 、甘肃山麦冬 [ Li r io p e kansuensi s (Batal .) C . H . Wright] 、禾 叶山麦冬[ Li r io pe g ram ini f olia (L .) Baker]和矮 小山麦冬[ Li r io p e ...

The fluorescence measurement is the key in observations of ultra high energy cosmic rays and in determinations of their primary energies in the TA experiment. Almost all fluorescence detectors of TA is in operation from June 2007. Here, we describe the characteristics of the telescopes and the status of the associated systems, and also present preliminary results from the first observation run ...