The present experiment was designed t investigate the role of posterior neocortex (areas 17, 18 and 18a) in the maintenance of performance on the radial maze. Following training to criterion on the 8-arm radial maze, rats received either sham operations, bilateral eye enucleations, lesions of posterior neocortex, or combined enucleations and lesions of posterior neocortex. While the enucleated ...

Social cooperation is a state in which people work together on shared activity from they both benefit, and the success of each person dependent everyone doing their part. Imagine, for example, basketball game all team members make effort cooperate to win game. To study this kind social lab, we used rats. We created special maze two rats must coordinate behavior as pair, moving through sections ...

Orbitofrontal cortical (OFC) and hippocampal (HPC) lesions in primates and rodents have been associated with impulsive behaviour. We showed previously that OFC- or HPC-lesioned rats chose the immediate low-reward (LR) option in preference to the delayed high-reward (HR) option, where LR and HR were associated with different spatial responses in a uniform grey T-maze. We now report that on a nov...

A disconnection procedure was used to test whether the hippocampus and anterior thalamic nuclei form functional components of the same spatial memory system. Unilateral excitotoxic lesions were placed in the anterior thalamic (AT) nuclei and hippocampus (HPC) in either the same (AT-HPC Ipsi group) or contralateral (AT-HPC Contra group) hemispheres of rats. The behavioral effects of these combin...

Abstract. Our cognition is structuring the informational layer, consisting of perception, anticipation, and action, and it should also be sustained on a physical basis. In this paper, we aim to explore the relationship between the informational layer and the physical layer from a dynamical systems point of view. As an example, the fluctuation of choice is investigated by using a simulated agent...

The ability of rats to learn the location of a hidden platform in a swim maze was compared in animals with excitotoxic lesions of the anterior or posterior (retrosplenial) cingulate cortex or radiofrequency lesions of the cingulum bundle or fimbria-fornix. Performance of this allocentric spatial task was unaffected by the posterior cingulate cortex lesions, while anterior cingulate cortex damag...

The experiment attempted to confirm the previous finding that hippocampal lesions in rats affected the information acquired by distant observation of the brightness difference of the T-maze arms, but left the information intact when it was gained by maze exploration. An alteration was introduced in the latter procedure allowing a complete elimination of olfactory stimuli, which might be utilize...

The effect of succinic salt diethylethanolamine fumaric ester on the cognitive abilities male CBA mice and outbred rats was studied. It found that test substance at doses 10 75 mg/kg in “Extrapolation escape task” has a positive short-term long-term memory animals, contributing to preservation reproduction information received. In “T-maze” test, both superior, it had comparable with reference d...