The scope and complexity of engineered systems are ever-increasing as burgeoning global markets, unprecedented technological capabilities, rising consumer expectations and ever-changing social requirements present difficult design challenges that often extend beyond the traditional engineering paradigm. These challenges require engineers and technical managers to treat the technological systems...

1 Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA, 2 Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA, 3 School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA and 4 Department of Genetics, Harvard Medical School, Boston, MA, USA * Corresponding author. Center for Cancer System...

Systems Engineering is a young field where most systems engineers are self educated older engineers. The large need for systems engineers in industry necessitates the creation of academic systems engineering groups where education and research is combined. We describe in this paper the ongoing effort in Norway to create such an academic systems engineering group as part of the Norwegian Centre ...

We review the lessons learned from problems with systems engineering over the past couple of decades and suggest that there are two effective strategies for overcoming them: (1) restricting the conventional systems engineering process to not-too-complex projects, and (2) adopting an evolutionary paradigm for complex systems engineering that involves rapid parallel exploration and a context desi...

(New York:Wiley, 1999), I get many questions about systems engineering, namely, what this field includes and excludes. A quick answer is, " take a look at the handbook. " A bit more of an elaborate answer, especially if people are interested in what we are doing at Georgia Tech, can be cast in terms of the manufacturing, logistics, transportation, and health systems programs available at ISyE. ...