A case is presented of pigmented villonodular synovitis involving three joints in a 7-year-old girl. The diagnosis was confirmed at surgery and by histology. The patient also exhibited a haemangioma of the upper lip and a congenital pulmonary stenosis of mild degree. Subtotal synovectomy of the right knee and of both ankles was performed. The lesion recurred in both ankles after 6 months. Revie...

Localized nodular synovitis is an uncommon entity with different presentations. It is proliferative disorder that originates from a frequently in the tendon sheaths of the small jo of localized nodular synovitis in a 30 years young man who came with complaints of discomfort in the knee joint. Swelling in the infrapatellar region was diagnosed on physical examination. imaging, a solitary ovoid m...

The chronic persistence of rheumatoid synovitis, an inflammation driven by activated T cells, macrophages, and fibroblasts causing irreversible joint damage, suggests a failure in physiologic mechanisms that down-regulate and terminate chronic immune responses. In vitro CD8(+)CD28(-)CD56(+) T cells tolerize APCs, prevent the priming of naive CD4(+) T cells, and suppress memory CD4(+) T cell res...

other serotypes, S. paratyphi B (S. schottmuelleri) is an uncommon human pathogen(l). Toxic synovitis of the hip refers to a transient, nonspecific, unilateral inflammatory arthritis involving the hip joint(2). It is a clinical diagnosis which is confirmed by excluding other causes for joint symptoms. In this communication, we describe a case of S. paratyphi B septicemia in a neonate presenting...

Chronic synovitis developed in the dorsal extensor sheath of the hand of a 25-year-old manufacturer of fibre glass reinforced boats and surfboards . Particles found in synovial fluid aspirates were similar in morphology and elemental content to unused fibre glass and particles found in dust from the workshop floor. It was concluded that hard disc grinding required during manufacture resulted in...

This paper reports the spontaneous development of synovitis in 'Old English' rabbits concurrent with serum IgM rheumatoid factor. Female rabbits developed lesions at a higher incidence than males (42% compared with 17%) and the pathology was of a more severe nature. In the female rabbits synovitis was associated with concurrent high serum IgM rheumatoid factor and high serum antibody levels to ...

Pigmented Villonodular Synovitis (PVNS) is an uncommon condition of the foot. PVS of the foot accounts for 2% of all cases. We present the case of a 26 year-old male who was found to have pigmented villonodular synovitis of the second metatarsophalangeal joint. Although a high incidence is reported in the literature, the patient underwent surgical excision with no known reoccurrence to date. Fi...

A patient with systemic lupus erythematosus (lupus) is described, in whom stress fractures of both legs developed, accompanied by swelling of both ankles. The swelling of the right ankle associated with fracture mimicked lupus synovitis, but resolved with healing of the fracture. On the left side the swelling represented true lupus synovitis coexistent with the tibial stress fracture. This pres...