نتایج جستجو برای: synovial sarcoma

تعداد نتایج: 88112  

2011
Lars Steinstraesser Reena Agarwal Ingo Stricker Hans-Ulrich Steinau Sammy Al-Benna

Synovial sarcoma is a rare type of soft tissue sarcoma that occurs mostly in young adults, and it is always regarded as a high-grade tumor. Here, we report the case of a 31-year-old German Caucasian male with synovial sarcoma of the wrist who was offered amputation at his local hospital. After referral to our Reference Centre for Soft Tissue Sarcoma, the quadruple approach of isolated limb perf...

Journal: :Foot & ankle international 2004
Loretta B Chou Martin M Malawer

Posterior tibial tendon dysfunction (PTIO) is a common disorder affecting the foot and ankle. In contrast, synovial sarcoma is uncommon. Because they often are slow growing, synovial sarcomas can be misdiagnosed as arthritis, bursitis, or synovitis. Synovial sarcoma also is one of the few soft-tissue tumors that can be painful. We describe two patients who had signs and symptoms similar to thos...

Journal: :Journal of Clinical Pathology 1998

2016
Ji-Hye Won Susie Chin Jai Soung Park Sang Hyun Paik Heon Lee Jang Gyu Cha Hwa Kyoon Shin Eun Suk Koh

Primary pleuropulmonary synovial sarcomas are rare soft tissue malignancies; combined metastatic involvement of the heart is extremely rare. In this case report, a 17-year-old female presented with a history of chest pain. Chest radiographs revealed a round mass in the left upper hemithorax, and computed tomography (CT) showed a well-defined heterogeneous enhancing mass abutting the pleura. A c...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011
Paul F Robbins Richard A Morgan Steven A Feldman James C Yang Richard M Sherry Mark E Dudley John R Wunderlich Azam V Nahvi Lee J Helman Crystal L Mackall Udai S Kammula Marybeth S Hughes Nicholas P Restifo Mark Raffeld Chyi-Chia Richard Lee Catherine L Levy Yong F Li Mona El-Gamil Susan L Schwarz Carolyn Laurencot Steven A Rosenberg

PURPOSE Adoptive immunotherapy using tumor-infiltrating lymphocytes represents an effective cancer treatment for patients with metastatic melanoma. The NY-ESO-1 cancer/testis antigen, which is expressed in 80% of patients with synovial cell sarcoma and approximately 25% of patients with melanoma and common epithelial tumors, represents an attractive target for immune-based therapies. The curren...

2012
Pei Xu Jianbin Chen

Synovial sarcoma is a rare malignant neoplasm that accounts for approximately 6% to 9% of all soft-tissue tumors. It occurs predominately in upper and lower extremities of young adults. We report the first case of a primary orbital synovial sarcoma in an 18-month-old girl.

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2005
E L Spurrell C Fisher J M Thomas I R Judson

AIMS Key prognostic factors at diagnosis of synovial sarcoma are well defined from the literature. There are few data regarding prognostic parameters in the setting of advanced disease. Our aim was to look specifically at a cohort of patients with advanced synovial sarcoma and to identify potential prognostic factors. PATIENTS AND METHODS One hundred and four patients with advanced synovial s...

Journal: :Journal of radiology case reports 2015
Robbert J de Haas Johannes J Bonenkamp Uta E Flucke Jacky W J de Rooy

Synovial sarcoma is the fourth most common type of soft-tissue sarcoma (following undifferentiated pleomorphic sarcoma, liposarcoma, and rhabdomyosarcoma), and should be considered a high-grade neoplasm with a high number of local recurrences and late metastases. Synovial sarcoma predominantly occurs in adolescents and young adults, and typically arises near the joints of the lower extremity. H...

2014
Yusuke Minami Shinji Kohsaka Masumi Tsuda Kazuhiro Yachi Nobuaki Hatori Mishie Tanino Taichi Kimura Hiroshi Nishihara Akio Minami Norimasa Iwasaki Shinya Tanaka

MicroRNA (miRNA) can function as tumor suppressors or oncogenes, and also as potential specific cancer biomarkers; however, there are few published studies on miRNA in synovial sarcomas, and their function remains unclear. We transfected the OncomiR miRNA Precursor Virus Library into synovial sarcoma Fuji cells followed by a colony formation assay to identify miRNAs to confer an aggressive tumo...

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