Background—The efficacy of cardiac pacing for prevention of syncopal recurrences in patients with neurally mediated syncope is controversial. We wanted to determine whether pacing therapy reduces syncopal recurrences in patients with severe asystolic neurally mediated syncope. Methods and Results—Double-blind, randomized placebo-controlled study conducted in 29 centers in the Third Internationa...

BACKGROUND The efficacy of cardiac pacing for prevention of syncopal recurrences in patients with neurally mediated syncope is controversial. We wanted to determine whether pacing therapy reduces syncopal recurrences in patients with severe asystolic neurally mediated syncope. METHODS AND RESULTS Double-blind, randomized placebo-controlled study conducted in 29 centers in the Third Internatio...

AIMS We prospectively correlated the results of tilt testing (TT) and adenosine triphosphate test (ATP) with the findings observed during a spontaneous syncopal relapse by means of an implantable loop recorder (ILR) in patients with a clinical diagnosis of neurally mediated syncope. METHODS AND RESULTS We included patients with three or more clinically severe syncopal episodes in the last 2 y...

OBJECTIVES We aimed to identify risk factors for recurrent syncope in children and adolescents with congenital long QT syndrome (LQTS). BACKGROUND Data regarding risk assessment in LQTS after the occurrence of the first syncope episode are limited. METHODS The Prentice-Williams-Peterson conditional gap time model was used to identify risk factors for recurrent syncope from birth through age...

Syncope is caused by a wide variety of disorders. Recurrent syncope as a complication of malignancy is uncommon and may be difficult to diagnose and to treat. Primary neck carcinoma or metastases spreading in parapharyngeal and carotid spaces can involve the internal carotid artery and cause neurally mediated syncope with a clinical presentation like carotid sinus syndrome. We report the case o...

a pulmonary embolus clogs the artery that provides blood supply to a part of the lung. the embolus not only prevents the exchange of oxygen and carbon dioxide but also decreases blood supply to the lung tissue itself, potentially causing the tissue to die (infarct). a 52-year-old man presented with syncope and anxiety. he had sinus tachycardia and dilated right ventricle with trabeculations. a ...

Syncope is a common presenting symptom, and is often a challenging diagnostic dilemma because of its various underlying causes. A careful initial clinical assessment with directed investigations is crucial in arriving at a presumptive diagnosis. Prolonged cardiac monitoring technologies have improved diagnostic accuracy in the more difficult cases.

UNLABELLED Syncope is a common complaint in clinical medical care. The etiology and mechanism can be complex. We report two cases experienced recurrent syncope to our emergency room without concomitant symptom. The image studies of both cases revealed apical neoplasms compress left common carotid artery with mediastinal lymphadenopathy and without cardiac/main artery trunk involved. After brain...

Gelastic syncope or laughter-induced syncope is a rare disease often misdiagnosed as narcolepsy or cataplexy. We report a 54-year-old man with syncopal episodes. Each episode started after laughter, leading to light-headedness with blurring of vision and loss of consciousness for a few seconds. The episodes resolved spontaneously. The treatment of gelastic syncope is the same as that for neural...

AIMS The aim of this study was to describe the head-up tilt (HUT) test and carotid sinus massage (CSM) responses, and the occurrence of syncope with coughing during HUT in a large cohort of patients. METHODS AND RESULTS A total of 5133 HUT were retrospectively analysed to identify patients with cough syncope. Head-up tilt followed by CSM were performed. Patients were made to cough on two sepa...