A new formulation, nanoprebiotics [e.g., phthalyl pullulan nanoparticles (PPNs)], was demonstrated to enhance the antimicrobial activity of probiotics Lactobacillus plantarum (LP)] in vitro through intracellular stimulation better than that by backbone prebiotics, which are commonly used. In this study, we aimed investigate whether combination would exert distinct effects as synbiotics vivo . S...

Introduction: Antibiotic- associated diarrhea is a common problem in pediatric population. There is growing interest in probiotics, probiotics and synbiotics for prevention of this complication because of their worldwide availability as dietary supplements. The aim of this study was to assess the efficacy of a synbiotic mixture in prevention of antibiotic- associated diarrhea.   Materials and M...

Mol. Nutr. Food Res. 2022, 66, 202101059 DOI: 10.1002/mnfr.202101059 The non-dairy based probiotics play the role of synbiotics because they have prebiotics in substrate matrix, which proliferates probiotic microorganisms by various mechanisms such as SCFAs, EPS and volatile compounds. Hence, synergetic effect on human health gut biota beneficial health. This is reported Dharmendra Kumar co-wor...

Serum samples were collected from each of 290 healthy dogs 6 months of age or older living in the Greater Metropolitan Manila (GMM) area over a 12 month period. These samples were examined by the Synbiotics DiroChek ® antigen capture test (San Diego, CA) for evidence of Dirofilaria immitis circulating antigen. At the time of the first sample 220 out of 290 examined were negative by the DiroChek...

The application of probiotics and prebiotics to the manipulation of the microbial ecology of the human colon has recently seen many scientific advances. The sequencing of probiotic genomes is providing a wealth of new information on the biology of these microorganisms. In addition, we are learning more about the interactions of probiotics with human cells and with pathogenic bacteria. An altern...

Intestinal microbiota play an important role in health and disease. The gut-liver axis provides for an interaction between bacterial components like lipopolysaccharide and hepatic receptors (Toll-like receptors). Dysbiosis and altered intestinal permeability may modulate this interaction and therefore result in hepatic disorders or worsening of hepatic disorders. Administration of health-promot...