Obsessive-compulsive disorder is characterized by obsessions or compulsions. Obsessions are unwanted and senseless thoughts, images, or impulses that occur repeatedly. Obsessions are experienced as unwanted and involuntary by the patient and can focus on such themes as contamination, aggression, orderliness, religion, sex:, doubt, or loss of possessions. Compulsions are ritualistic but seemingl...

In this case series we report four cases of patients with Down syndrome with symptoms consistent with obsessive compulsive disorder. Each patient experienced substantial reduction in compulsive behaviors with pharmacotherapy of an SSRI alone or with the addition of risperidone to SSRI therapy. None of the patients experienced significant side effects. This small case series supports the use of ...

Obsessive-compulsive symptoms are common in patients with bipolar disorders. This comorbid condition complicates the clinical treatment of the two disorders, so identifying these individuals is important. We discuss the comorbid occurrence of obsessive-compulsive disorder and bipolar disorder, introduce possible etiological mechanisms that could result in this common comorbid condition, discuss...

Neuroimaging studies have indicated abnormalities in cortico-striato-thalamo-cortical circuits in obsessive-compulsive disorder patients, but results have not been consistent. Since there are significant sex differences in human brain anatomy and obsessive-compulsive symptomatology and its developmental trajectories tend to be distinct in males and females, we investigated whether sex is a pote...

Introduction: Despite the common sociocultural background in the Arab world, considerable differences exist between its different countries. Aim of the Study: The study was conducted aiming at evaluating the impact of obsessive compulsive disorder on patients’ life in two relatively different Arab cultures and the implication of these cultures on OCD presentation and symptomatology. Subjects an...

OBJECTIVE The primary objective of this study was to examine neurological soft signs in patients with obsessive-compulsive disorder compared with patients with schizophrenia and a control group in the Indian setting. The secondary objective was to find any correlation between age at onset and neurological soft signs scores, as well as that between severity of obsessive-compulsive disorder sympt...

Wilson's disease, a disorder of copper metabolism, is known to be associated with psychiatric symptoms. Psychiatrists see about 20% of these cases before they are labeled as Wilson's disease. Reports of these patients treated mistakenly as primary psychiatric illnesses exist in literature. This report thus emphasizes a thorough underpinning in this disease on the part of psychiatrists in order ...

Anxiety is one of the most common psychopathological symptoms. It based on feeling a strong threat without triggering real stimulus. They are often accompanied by somatic symptoms, making it difficult to function normally and carry out daily activities. The causes anxiety disorders include genetic environmental factors. can take form of, but not limited to, generalized disorder panic disorder, ...

The data provided here related to our research article (Chen et al., 2016) [1]. We provide whole-brain intrinsic functional connectivity patterns in obsessive-compulsive disorder at resting-state [1]. This article also provides supplementary information to our research article, i.e., between - group comparisons of the effect of selective serotonin reuptake inhibitors (SSRIs) and combined depres...