Many species of gram-negative bacteria communicate by synthesizing, secreting, and responding to N-acylhomoserine lactones (AHLs), a mechanism termed quorum sensing. Several investigations have characterized numerous AHL-degrading enzymes (AiiA lactonases) encoded by environmental isolates of Bacillus spp. The Burkholderia thailandensis quorum system is comprised of at least three AHL synthases...

Numerous gram-negative bacteria communicate and regulate gene expression through a cell density-responsive mechanism termed quorum sensing (QS), which involves the synthesis and perception of diffusible N-acyl-homoserine lactones (AHL). In this study we genetically and physiologically characterized the Burkholderia thailandensis DW503 QS network. In silico analysis of the B. thailandensis genom...

Swarming is a particular type of motility that is promoted by flagella and allows bacteria to move rapidly over and between surfaces and through viscous environments. Swarming must confer considerable survival benefit, as a heterogeneous group of bacteria exhibit this form of motility, including strains of Aeromonas, Azospirillum, Bacillus, Burkholderia, Chromobacterium, Clostridium, Escherichi...

Antimicrobial peptides (APs) are important components of the innate defenses of animals, plants, and microorganisms. However, some bacterial pathogens are resistant to the action of APs. For example, Proteus mirabilis is highly resistant to the action of APs, such as polymyxin B (PM), protegrin, and the synthetic protegrin analog IB-367. To better understand this resistance, a transposon mutage...

We investigated the transcriptional responses of Pseudomonas aeruginosa under phosphate-deficient (0.2 mM) conditions compared to phosphate sufficiency (1 mM). This elicited enormous transcriptional changes in genes related to phosphate acquisition, quorum sensing, chemotaxis, toxin secretion, and regulation. This dysregulation also led to increased virulence-associated phenotypes, including sw...

Quorum sensing (QS) is a type of cell-to-cell communication that influenced by an increase in signaling molecules known as autoinducers, which correlated to the density microbial communities. In this review, we aim discuss and provide updates on different used Escherichia coli, such acyl-homoserine lactone (AHL), autoinducer-2 (AI-2), indole influence key phenotypes antibiotic drug resistance, ...