Adeno associated virus (AAV) is a non-pathogenic dependent parvovirus with a broad host range, capable of high levels of transduction and stable integration into the host cell genome. We have investigated the potential for using AAV as a vector for gene transfer into glial cells of the human fetal nervous system. Recombinant AAV vectors expression either the reporter gene beta-galactosidase or ...

The goal of this work is to provide an original (semi-automatic) annotation framework titled SVG-to-RDF which converts a collection of raw Scalable vector graphic (SVG) images into a searchable semantic-based RDF graph structure that encodes relevant features and contents. Using a dedicated knowledge base, SVG-to-RDF offers the user possible semantic annotations for each geometric object in the...

MOTIVATION Drawing genomic features in attractive and informative ways is a key task in visualization of genomics data. Scalable Vector Graphics (SVG) format is a modern and flexible open standard that provides advanced features including modular graphic design, advanced web interactivity and animation within a suitable client. SVGs do not suffer from loss of image quality on re-scaling and pro...

OBJECTIVES The purpose of this study was to define the pre-operative angiographic variables that could influence graft patency and flow pattern. BACKGROUND Saphenous vein grafts (SVG) and pedicled right gastroepiploic artery (RGEA) grafts are routinely used to revascularize the right coronary artery (RCA). Little is known about the predictive value of objective pre-operative angiographic para...

This chapter aims at introducing method for load balancing spatial analysis into XML/GML/SVG-based WebGIS. We propose that the decision on where to execute spatial query operations (server side or browser side) should be based on the network communication cost versus the computational cost. This chapter mainly focuses on the network communication cost. After analyzing the workflow of spatial an...

Autologous saphenous vein bypass grafts (SVG) are frequently compromised by neointimal thickening and subsequent atherosclerosis eventually leading to graft failure. Hyaluronic acid (HA) generated by smooth muscle cells (SMC) is thought to augment the progression of atherosclerosis. The aim of the present study was (1) to investigate HA accumulation in native and explanted arterialized SVG, (2)...

Saphenous vein graft (SVG) angioplasty is associated with frequent periprocedural complications due to distal embolization and a high risk of restenosis. The purpose of this single-center, retrospective study was to determine the distal embolization incidences and outcomes of stenting for SVG lesions and percutaneous angioplasty for in-stent restenosis of these SVGs. We studied 48 consecutive p...

In the context of enterprise architecture management, complex diagrams proprietary software systems are often created. Working with these is not self-explanatory, as multiple layers information contained in overview. Changing design and style supported within hierarchical structure impossible outside original product. Separating content from provides a solution to this problem. The use scalable...

BACKGROUND There are limited data on comparison of contemporary drug-eluting stent (DES) platforms, previous generation DES, and bare-metal stents (BMS) for percutaneous coronary intervention in saphenous vein grafts (SVG). We aimed to assess clinical outcomes following percutaneous coronary intervention to SVG in patients receiving bare-metal stents (BMS), first-generation DES, and newer gener...

OBJECTIVES The purpose of this study was to compare early and late clinical outcomes in diabetic and nondiabetic patients after stent implantation in saphenous vein grafts (SVG). BACKGROUND Patients with diabetes mellitus have less favorable acute and long-term outcomes after stent implantation in native coronary arteries. The impact of diabetes on SVG stenting, however, is not known. METHO...