Melanoma is a malignant tumor with high invasive and metastatic properties. Though radiation is the major therapy for melanoma, its radio-resistance has been shown to severely influence the clinical outcome. So it is imperative to enhance the sensitivity of uveal melanoma cells to radiotherapy. Previously, we found that the cell cycle of 92-1 uveal melanoma cells was suspended and remained unch...

The effect of illumination on the viscosity of titania suspensions in silicone oil (insulating medium) and an aqueous buffer (conducting medium) was investigated. Commercially available P25 anatase titania was suspended at a volume fraction of 0.5%. A 12.3% increase in viscosity was observed when silicone oil suspension was used as the medium, while a 2.47% decrease in viscosity was observed fo...

NIH 3T3 cells cultured in suspension fail to express cyclin A and hence cannot enter S phase and divide. We show that loss of cell adhesion to substratum abrogates cyclin A gene expression by blocking its promoter activity through the E2F site that mediates its cell cycle regulation in adherent cells. In suspended cells, G0-specific E2F complexes remain bound to the cyclin A promoter. Overexpre...

Training aids form a fundamental component of gymnastic training. Previous research has shown how a suspended aid changes biomechanics of circles on pommel horse. Building on these findings, the aim of the current study was to examine the influence of a modified use of the aid through the suspension of the gymnast at different positions. Discriminative biomechanical variables, which were identi...

The original LIGO suspension control system [1] used analog circuitry to implement the closed loop damping required for local control of each of the suspended optics. As installation and commissioning activities have progressed, it has become apparent that these controls do not provide the performance and flexibility that will be required for operation of the interferometers. Recent development...

Kelussia odoratissima Mozaff. belonging to the Apiaceae family, is well known for its medicinal and nutritional importance, endemic to Iran. Seed dormancy is a major problem present in Kelussia odoratissima leading to low germination percentage; thus, improvement of seed germination and breaking seed dormancy is important. Piriformospora indica, a root-colonizing endo...

Purpose: The goal of this work is to reduce the effect dynamic loads on mine timbering through use elastic devices contained in monorail suspension and justify their parameters. Methods materials: article considers developed mathematical model vertical oscillations track, which allows setting interconnection between rolling stock parameters suspension. At under harmonic disturbing force caused ...

There is a strong scientific case for the study of gravitational waves at or below the lower end of current detection bands. To take advantage of this scientific benefit, future generations of ground based gravitational wave detectors will need to expand the limit of their detection bands towards lower frequencies. Seismic motion presents a major challenge at these frequencies and vibration iso...