Gonadal steroid 17?-estradiol (E2) exerts rapid, non-genomic effects on neurons and strictly regulates learning memory through altering glutamatergic neurotransmission synaptic plasticity. However, its AMPARs are not well understood. Here, we analyzed the rapid effect of E2 using single-molecule tracking super-resolution imaging techniques. We found that rapidly decreased surface movement AMPAR...

micropolar plasticity provides the capability to carry out post-failure simulations of geo-structures due to microstructural considerations and embedded length scale in its formulation. an essential part of the numerical implementation of a micropolar plasticity model is the integration of the rate constitutive equations. efficiency and robustness of the implementation hinge on the type of inte...

Sheet metal forming as well mechanical joining demand increasingly accurate and efficient material modelling to capture large deformations, the inherent sheet orthotropy even process-induced damage, which is expected be influential. To account for strains additive logarithmic strain space utilised that enables a straightforward incorporation of plastic anisotropy, herein modelled by Hill48 yiel...