Electronic biosensors offer a viable alternative to optical biosensors for the rapid, specific, and sensitive detection of DNA. We are utilizing an electrolyte-oxide-semiconductor (EOS) biosensor system on a SiO2/Si surface for impedimetric detection of DNA. Detection in this system is based on the intrinsic negative charge of DNA. Hybridization of target DNA to the probe-functionalized semicon...

The effects of chemical and structural surface heterogeneity on the CH4 adsorption behaviour on microporous carbons have been investigated using a hybrid theoretical approach, including the use of density functional theory (DFT), molecular dynamics (MD), and grand canonical Monte Carlo (GCMC) simulations. Bader charge analysis is first performed to analyze the surface atomic partial charges. Th...

Nanostructured porous silicon (nanoPS) basically consists in a network of silicon nanocrystals with high specific surface. Its intrinsic high surface reactivity makes nanoPS a very suitable material for the development of biosensors. In this work, the surface of nanoPS was functionalized by the use of (3-aminopropyl)triethoxysilane solutions in toluene. Escherichia coli (E. coli) antibodies wer...

This review focuses on the recent development and various strategies in the preparation, microstructure, and magnetic properties of bare and surface functionalized iron oxide nanoparticles (IONPs); their corresponding biological application was also discussed. In order to implement the practical in vivo or in vitro applications, the IONPs must have combined properties of high magnetic saturatio...

A mechanical method for efficient replication of DNA microarrays is described. The approach consists of three steps. First, a master DNA microarray consisting of single-stranded DNA elements is exposed to a solution containing the biotin-functionalized complement of each array element. Following hybridization, a replica surface modified with streptavidin is brought into contact with the master....

In this contribution, Fe3O4 magnetic nanoparticles (MNPs) have been functionalized with a tetraphosphonate cavitand receptor (Tiiii), capable of complexing N-monomethylated species with high selectivity, and polyethylene glycol (PEG) via click-chemistry. The grafting process is based on MNP pre-functionalization with a bifunctional phosphonic linker, 10-undecynylphosphonic acid, anchored on an ...

Nanostructure fabrication from block copolymers is discussed in this review paper. Particularly, novel approaches for the Ž . Ž . construction of functionalized poly ethylene glycol PEG layers on surfaces were focused to attain the specific adsorption of a target protein through PEG-conjugated ligands with a minimal non-specific adsorption of other proteins. Furthermore, surface organization of...

Palladium (Pd) is considered as ideal hydrogen sensing material due to its properties as high sensitivity and selectivity to hydrogen gas, fast response and reversible room temperature operation.Silicon nanowire (SiNW) functionalized with Pd based hydrogen gas nanowire sensor having quantum confinement effect and high sensitivity because of high surface to volume ratio of SiNW. This paper highl...

In this study, we investigated the effect of (ethylene glycol) (PEG) and PEG-oleylamine (OAm) functionalization on the skin permeation property of gold nanoparticles (GNS) in vivo. Chemisorption of polymers onto GNS was verified by a red shift in the ultraviolet-visible spectrum as well as by a change in the nanoparticle surface charge. The physicochemical properties of pristine and functionali...

We report that oxidized multiwalled carbon nanotubes (MWCNTs) can be synchronously dispersed and functionalized in TiO2 sol via an in situ sol-gel process. Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, and atomic force microscopy (AFM) were used to characterize the functionalized MWCNTs. The results revealed that the hydrolysis and condensat...