BACKGROUND/AIM Pro-free radical oxidative stresses, as well as regulatory factors, are believed to be the key players in the development of diabetes and heart-related disorders such as myocardial infarction. The aim of the present study was to highlight the role of oxidative stress-responsive factors (reactive oxygen species [ROS], super oxide dismutase [SOD], and calpain-1) in type 2 diabetes ...

Madecassoside (MA), one of the principle terpenoids in Centella asiatica, has shown protect effect on isolated rat hearts and isolated cardiomyocytes against reperfusion injury in our previous studies. The aim of this study is to investigate if MA also protected against myocardial ischemia-reperfusion injury in vivo. The ischemia infarction model was established in rats. Left ventricular functi...

Understanding the salinity stress mechanisms is essential for crop improvement and sustainable agriculture. Salinity prepotent abiotic compared with other stresses that decrease growth development, reducing production creating food security-related threats. Therefore, input of metal oxide nanoparticles (NPs) such as zinc (ZnO-NPs) can improve salt tolerance in plants, especially early stage gro...

BACKGROUND Extracts of plants have been considered as sources of natural antioxidant agents. In this study, we aimed to explore the antioxidant capacity of the aqueous root extract of Asparagus cochinchinensis (Lour.) Merr. METHODS Using vitamin C (Vc) as a positive control, we analyzed the aqueous root extract of A. cochinchinensis free radical scavenging ability in vitro. We also establishe...

The present study was designed to investigate the ameliorating effect of aqueous extract of C. dactylon on carbofuran induced oxidative stress (OS) and alterations in the activity of acetylcholinesterase (AChE) in the brain of rats. Vitamin C was used as a positive control. Wistar rats were administered with single sub-acute oral dose (1.6 mgkg-1 b.wt.) of carbofuran for 24 h. The OS parameters...

Oxyradicals are chemical species with an unpaired electron in one of their orbits. Production of oxyradicals occurs throughout the body during cellular metabolism [l]. A complex antioxidant system exists to regulate levels of oxyradicals as excessive production or ineffective removal can result in cellular damage. The antioxidant enzymes present indude superoxide dismutase (SOD), glutathione pg...

The discus is a very popular and expensive aquarium fish belonging to the family Cichlidae, genus Symphysodon, formed by three Amazon basin endemic species: Symphysodon aequifasciatus, S. discus and S. tarzoo. The taxonomic status of these fish is very controversial, with a paucity of molecular research on their population genetic structure and species identification. Information on molecular g...

We investigated the antioxidative activity of LX519290, a derivative of l-allo threonine, in vitro and in vivo. To evaluate the antioxidative activity of LX519290, we performed several in vitro assays (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical-scavenging assays, a ferric reducing antioxidant power assay, cupric-reducing antio...

Changes in freezing injury percentage, lipid peroxidation (malonaldehyde formation), antioxidant enzymes activity and proline content were monitored in the leaves of olive cvs. ‘Fishomi’ and ‘Roughani’ under diff erent freezing temperatures (-5, -10, -15 and -20°C for 10 h). Th e results showed that freezing injury (determined by electrolyte leakage analysis) and malonaldehyde (MDA) content of ...

A method of Type II alveolar epithelial cell culture in aerobiosis has been developed. Isolation of Type II cells was performed by digesting guinea-pig lung tissue with crude trypsin and elastase and using discontinuous Percoll density gradients. The Type II cells, as identified by light and electron microscopy, were cultured in aerobiosis for up to six days, in direct contact with the atmosphe...