The ability to deliver therapeutic agents to a patient in a pulsatile or staggered release profi le has been a major goal in drug delivery research recently. This review will cover methods that have been developed to control drug delivery profi le with different polymeric systems. Externally and internally controlled systems will be considered, including a range of technologies like preprogramm...

Tomography refers to the synthesis of sectional images or slices from external measurements of a spatially varying function. Line integrals are the most common external measures, which are also known as projections. Availability of multiple projections at diierent orientations allows accurate recovery of the originating function. Because practical implementation of tomography typically requires...

We describe the characteristics and evolution of the magnetic field and chromospheric emission in an active region core observed by the Solar Optical Telescope (SOT) on Hinode. Consistent with previous studies, we find that the moss is unipolar, the spatial distribution of magnetic flux evolves slowly, and that the magnetic field is only moderately inclined. We also show that the field line inc...

We have observed high-resolution intensity spectra near the Fe i 1564.8 nm line at a single umbral point corresponding to the darkest position in over 900 sunspots from 1998 through 2005. From these data we determine that the maximum sunspot magnetic fields have been decreasing at about 52 G yr . The same data set shows a concurrent increase in the normalized umbral intensity from 0.60 to 0.75 ...