background staphylococcus aureus is a significant pathogen that can colonize the nares of different animals, causing a wide range of infections in various hosts. objectives we intended to determine the prevalence of s. aureus in the nasal cavity of healthy ruminants and also to investigate the presence of antibiotic resistance genes. materials and methods in the present study, healthy cattle (n...

conclusions induction of coccoid form of p. aeruginosa may be one of the important reasons for antibiotic treatment failure; therefore, prescribed dose of antibiotics should be carefully managed to prevent increasing antibiotic resistance and coccoid bacteria induction. results all used antibiotics at sub mic concentration had capability to induce coccoid bacteria. the highest rate of induced c...

conclusions the results of this study suggest that e. hebecarpa extracts can be used to inhibit the planktonic and biofilm forms of these selected bacteria. objectives in an effort to combat these industrial and medical bacterial biofilm problems, our study aims to determine the antimicrobial effect of euphorbia hebecarpa. materials and methods the inhibition efficiency of alcoholic extracts on...

background hospital patients who are nasal carriers of methicillin-resistant staphylococcus aureus (mrsa) are a high-risk potential threat to themselves and other hospitalized patients. the high antibiotic resistance of these isolates renders the treatment of related infections difficult. objectives the present study, for the first time investigated the prevalence of mrsa isolates in nasal carr...

conclusions vancomycin, but not teicoplanin, can be considered an effective antibiotic of choice for controlling infections caused by mdr cons in gorgan, depending on the bacterial species. background coagulase-negative staphylococci (cons) are clinically important, especially in nosocomial and neonatal infections. the increasing emergence of glycopeptide-resistant cons has made these agents th...

background and objective: diabetes mellitus is one of the main problems in health systems in the world. diabetic foot infections (dfi) is one of the main complications and the most cause  of non-traumatic lower limb amputation .this study aimed to determine the prevalence of bacteria involved in dfi and their antibiotic resistance in patients with dfi diagnosis. patients and methods: this desc...

BRAF is an important component of MAPK cascade. Mutation BRAF, in particular V600E, leads to hyperactivation the pathway and uncontrolled cellular growth. Resistance selective inhibitors mutated a major obstacle against treatment many cancer types. In this work, series new (imidazo[2,1-b]thiazol-5-yl)pyrimidine derivatives possessing terminal sulfonamide moiety were synthesized. Pan-RAF inhibit...