BACKGROUND Among Canadians aged 15 to 24, the rate of depression is higher than at any other age, and suicide is the second leading cause of death. The current study provides detailed information about depression and suicidal ideation among young Canadians, including their use of mental health support. DATA AND METHODS Data from the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH...

BACKGROUND Research has documented significant associations between life stress, especially interpersonal stress, and suicidal ideation in adolescents. Little is known about variables that explain the association between interpersonal stress and suicidal ideation. METHODS The present study evaluated a conceptual model in which interpersonal stress (chronic and episodic) predicted suicidal ide...

Treatment-emergent suicidal ideation and behavior are ongoing concerns with antidepressants. Vilazodone, currently approved for the treatment of major depressive disorder (MDD) in adults, has also been evaluated in generalized anxiety disorder (GAD). Post-hoc analyses of vilazodone trials were carried out to examine its effects on suicidal ideation and behavior in adults with MDD or GAD. Data w...

BACKGROUND Developmental adversities may be risk factors for adult suicidal behavior, but this relationship has rarely been studied prospectively. The present study examined the association between childhood adversities and new onset suicidal ideation and attempts in an adult population-based sample. METHOD The study used a large community mental health survey (the Netherlands Mental Health S...

BACKGROUND Whereas prevalence of suicidal expressions among young people is fairly similar in different countries, less is known about associated risk factors. This study compares young people in Nicaragua and Cambodia to examine if the pattern of association between mental health problems and suicidal expressions differs. METHODS 368 and 316 secondary school students, from each country respe...

Suicidal behaviors are prevalent among young people. Numerous risk factors have been implicated in their development. In the framework of the longitudinal Mannheim Study of Children at Risk, 311 young adults (143 males, 168 females) aged 19-23 years were investigated in order 1) to determine the significance of different risk factors during development in predicting suicidal behaviors in young ...

INTRODUCTION Feelings that life is not worth living and thoughts of suicide are common in psychiatric patients, particularly in depressives (Beck, 1967).Very littleinformationis available, however, regarding the occurrence of suicidal feelings in the general population. In contrast, the epidemiology of completed suicide has received extensive study (Dublin, 1963), and therehave beensome epidemi...

OBJECTIVE The serotonin transporter (5-HTT) genes are major candidate genes for modulating the suicidal behavior. We investigated the association between serotonin transporter polymorphisms and suicidal behavior in patients with major depressive disorder (MDD). METHODS Serotonin transporter intron 2 VNTR polymorphism (5-HTTVNTR) and serotonin transporter linked polymorphic region polymorphism...

It is known that suicidal behaviour has multiple causes. If triggers could be mainly attributed to environmental factors, predisposition could be associated with early stressors on one side such as childhood adversities and genetic predisposition. No convincing animal model of suicide has been produced to date. The study of endophenotypes has been proposed as a good strategy to overcome the met...

Antidepressants and antipsychotics can cause side effects in various organs and organic systems, and some (and) in the central nervous system, which can also be clinically manifested by suicidal behavior as well. Tricyclic antidepressants particularly of imipramine and clomipramine can have pro-suicidal effect, which is believed to be the consequence of their own hypothetic asynchronous cogniti...