نتایج جستجو برای: subthalamic nucleus stn

تعداد نتایج: 113577  

2012
Naoki Nakano Mamoru Taneda Akira Watanabe Amami Kato

Background. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is one of the standard surgical treatments for advanced Parkinson's disease. However, it has been difficult to accurately localize the stimulated contact area of the electrode in the subthalamic nucleus and its adjacent structures using a two-dimensional atlas. The goal of this study is to verify the real and detailed loc...

2012
Max C. Keuken Harry B. M. Uylings Stefan Geyer Andreas Schäfer Robert Turner Birte U. Forstmann

The prevailing academic opinion holds that the subthalamic nucleus (STN) consists of three parts, each anatomically distinct and selectively associated with cognitive, emotional, or motor functioning. We independently tested this assumption by summarizing the results from 33 studies on STN subdivisions in human and nonhuman primates. The studies were conducted from 1925 to 2010 and feature thre...

Journal: :Movement disorders : official journal of the Movement Disorder Society 2010
Adam Zaidel Hagai Bergman Ya'acov Ritov Zvi Israel

There is a consensus that in Parkinson's disease, the extent of preoperative levodopa responsiveness predicts the efficacy of subthalamic nucleus deep brain stimulation (STN DBS). However, this may be the result of statistical methods and primary assumptions. We were able to reproduce previously published correlation results on our data (N = 49 patients). Yet, these same results were demonstrat...

Journal: :Brain and language 2017
Julie Péron Olivier Renaud Claire Haegelen Lucas Tamarit Valérie Milesi Jean-François Houvenaghel Thibaut Dondaine Marc Vérin Paul Sauleau Didier Grandjean

Using intracranial local field potential (LFP) recordings in patients with Parkinson's disease (PD) undergoing deep brain stimulation (DBS), we explored the electrophysiological activity of the subthalamic nucleus (STN) in response to emotional stimuli in the auditory modality. Previous studies focused on the influence of visual stimuli. To this end, we recorded LFPs within the STN in response ...

Journal: :Brain and language 2015
Christina Tremblay Joël Macoir Mélanie Langlois Léo Cantin Michel Prud'homme Laura Monetta

The effects of subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson's disease (PD) on different language abilities are still controversial and its impact on high-level language abilities such as metaphor comprehension has been overlooked. The aim of this study was to determine the effects of STN electrical stimulation on metaphor comprehension and language abilities such as lexic...

Journal: :Neurology 2008
C Moreau L Defebvre A Destée S Bleuse F Clement J L Blatt P Krystkowiak D Devos

BACKGROUND Severe gait disturbances and freezing episodes (frequently resistant to optimal dopaminergic treatment) often appear in advanced Parkinson disease (PD). Even several years after initiation, high-frequency subthalamic nucleus deep brain stimulation (STN-DBS) is still very effective for controlling segmental symptoms. However, there are no long-term data on the management of gait disor...

Journal: :Nonlinear Dynamics 2023

Dysfunction of basal ganglia is associated with the pathogenesis Parkinson's disease including alteration firing rate and excessive beta-band (13-30 Hz) synchronization activity. Neuronal heterogeneity enriches dynamics external globus pallidus (GPe), especially showing significant differences in alterations under pathological state. The precise mechanism underlying these neural signatures rema...

Journal: :Brain Stimulation 2023

Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective surgical treatment for Parkinson’s disease (PD), alleviating motor symptoms and restoring patients’ quality life. Research into long-term effects DBS on human lacking. This study aims to investigate neuroanatomical neurochemical alterations induced by chronic stimulations STN, correlate these changes with cli...

Journal: :Neuroscience 2005
D Centonze P Gubellini S Rossi B Picconi A Pisani G Bernardi P Calabresi C Baunez

Subthalamic nucleus (STN) is a target of choice for the neurosurgical treatment of Parkinson's disease (PD). The therapeutic effect of STN lesion in PD is classically ascribed to the rescue of physiological activity in the output structures of the basal ganglia, and little is known about the possible involvement of the striatum. In the present study, therefore, we electrophysiologically recorde...

2017
Damian M Herz Huiling Tan John-Stuart Brittain Petra Fischer Binith Cheeran Alexander L Green James FitzGerald Tipu Z Aziz Keyoumars Ashkan Simon Little Thomas Foltynie Patricia Limousin Ludvic Zrinzo Rafal Bogacz Peter Brown

Optimal decision-making requires balancing fast but error-prone and more accurate but slower decisions through adjustments of decision thresholds. Here, we demonstrate two distinct correlates of such speed-accuracy adjustments by recording subthalamic nucleus (STN) activity and electroencephalography in 11 Parkinson's disease patients during a perceptual decision-making task; STN low-frequency ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید