نتایج جستجو برای: subthalamic nucleus
تعداد نتایج: 112660 فیلتر نتایج به سال:
Electrical stimulation of the subthalamic nucleus is an established treatment for patients with advanced Parkinson’s disease with pharmacologically un responsive fl uctuations. Compared with pharmacological treatment, subthalamic neurostimulation signifi cantly improves motor symptoms, particularly during the phases of poor response to drug treatment, and reduces the severity of dyskinesias. Im...
Recent pathophysiological models of Parkinson's disease have led to new surgical approaches to treatment including deep brain stimulation (DBS) and lesioning of basal ganglia structures. Various measures of upper limb akinesia were assessed in 6 patients with bilateral DBS of the internal pallidum and 6 with DBS of the subthalamic nucleus. Stimulation improved a number of aspects of motor funct...
The present study analyses the anatomical arrangement of the projections linking the Wistar rat parafascicular thalamic nucleus (PF) and basal ganglia structures, such as the striatum and the subthalamic nucleus (STN), by using neuroanatomical tract-tracing techniques. Both the thalamostriatal and the striato-entopeduncular projections were topographically organized, and several areas of overla...
#### Notable in Neurology This Week This issue features an article that examines the long-term effects of deep brain stimulation subthalamic nucleus on motor complications patients with Parkinson disease; another investigates how death by neurologic criteria protocols vary across pediatric hospitals United States. A featured Contemporary Issues Practice, Education, & Research reports a program...
BACKGROUND/AIMS Deep brain stimulation (DBS) is widely used to treat motor symptoms in patients with advanced Parkinson's disease. The aim of this study was to investigate the anatomical aspects of the electric field in relation to effects on speech and movement during DBS in the subthalamic nucleus. METHODS Patient-specific finite element models of DBS were developed for simulation of the el...
The neural substrates that enable individuals to achieve their fastest and strongest motor responses have long been enigmatic. Importantly, characterization of such activities may inform novel therapeutic strategies for patients with hypokinetic disorders, such as Parkinson's disease. Here, we ask whether the basal ganglia may play an important role, not only in the attainment of maximal motor ...
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