Genomic sequencing and structural genomics produced a vast amount of sequence and structural data, creating an opportunity for structure-function analysis in silico [Radivojac P, et al. (2013) Nat Methods 10(3):221-227]. Unfortunately, only a few large experimental datasets exist to serve as benchmarks for function-related predictions. Furthermore, currently there are no reliable means to predi...

Multiple-output regression models require estimating multiple parameters, one for each output. Structural regularization is usually employed to improve parameter estimation in such models. In this paper, we present a multiple-output regression model that leverages the covariance structure of the latent model parameters as well as the conditional covariance structure of the observed outputs. Thi...

Measures of network structural integrity useful in the analysis and synthesis of power systems are discussed. Signal flow methodology is applied to derive an expression for the paths between sources and sinks in a power network. Connectivity and reach ability properties of the network are obtained using the minors of a modified connectivity matrix. Node-connectivity, branch connectivity and mix...

fept nanoparticles with thermally stable room-temperature ferromagnetism are investigated. the monodisperse nanoparticles are prepared by chemical synthesis and a salt-matrix annealing technique. structural and magnetic characterizations confirm the phase transition from the disordered face-centered cubic structure. in this paper, 3 nm fept nanoparticles are first synthesized by superhydride re...

where x is a vector of displacements of structural coordinates, M is a positive definite mass matrix, C is a non-negative definite damping matrix, and K is a non-negative definite stiffness matrix. The nonlinear restoring forces are given in R(x, ẋ) and f ext(t) is a vector of external dynamic loads. At any point in time, t = ti+1 = (i+ 1)h, we may solve for the accelerations in terms of the di...

Zinc oxide nanoparticles have been synthesized by chemical reaction method.  Polyvinyl alcohol (PVA) composite film filled with nanometric, monodispersed zinc oxide nano particles prepared by PVA solution and nanozinc oxide. Polymer blend with ZnO nanoparticle composite film has prepared by casting technique.  The property of nano composites depends greatly on the chemistry of polymer matrices....

Zinc oxide nanoparticles have been synthesized by chemical reaction method.  Polyvinyl alcohol (PVA) composite film filled with nanometric, monodispersed zinc oxide nano particles prepared by PVA solution and nanozinc oxide. Polymer blend with ZnO nanoparticle composite film has prepared by casting technique.  The property of nano composites depends greatly on the chemistry of polymer matrices....

in the present study, modelling and vibration analysis of carbon nanotubes/ fiber/ polymer composite microplates are investigated. the governing equations of the carbon nanotubes/ fiber/ polymer composite microplates are derived based on first order shear deformation plate theory, rather than other plate theories, due to accuracy and simplicity of polynomial functions. the modified couple stres...