While the biological functions of most of the secondary metabolites made by streptomycetes are not known, it is inconceivable that they do not play an adaptive ecological role. The biosynthesis of secondary metabolites under laboratory conditions usually occurs in a growth phase or developmentally controlled manner, but is also influenced by a wide variety of environmental and physiological sig...

Well-characterized promoters are essential tools for metabolic engineering and synthetic biology. In Streptomyces coelicolor, the native kasOp is a temporally expressed promoter strictly controlled by two regulators, ScbR and ScbR2. In this work, first, kasOp was engineered to remove a common binding site of ScbR and ScbR2 upstream of its core region, thus generating a stronger promoter, kasOp3...

Sanchez-Marroquin, A. (University of Mexico, México D.F.). Constancy of characteristics in the streptomycetes. J. Bacteriol. 83:1183-1192. 1962.-A total of 150 Streptomyces strains isolated from soil was studied during a 3-year period in regard to constancy and variation of the following characteristics: sporophore micromorphology, color of the aerial and substrate mycelium, surface configurati...

A study of the bacteriolytic properties of streptomycetes has progressively uncovered the production by these microorganisms of a large number of different enzymes acting upon various bacterial constituents, especially on some of them located in the cell wall Although the mechanism of the bacteriolysis is far from being completely elucidated at present, it can, however, be stated that, in two i...