The white matter pathways of the brain can be reconstructed as 3D polylines, called streamlines, through the analysis of diffusion magnetic resonance imaging (dMRI) data. The whole set of streamlines is called tractogram and represents the structural connectome of the brain. In multiple applications, like group-analysis, segmentation, or atlasing, tractograms of different subjects need to be al...

BACKGROUND Previous studies reported reduced volumes of many brain regions for temporal lobe epilepsy (TLE). It has also been suggested that there may be widespread changes in network features of TLE patients. It is not fully understood, however, how these two observations are related. METHODS Using magnetic resonance imaging data, we perform parcellation of the brains of 22 patients with lef...

Streamline advection has proven an eeective method for visualizing vector ow eld data. Traditional streamlines do not, however, provide for investigating the coarser-grained features of complex datasets, such as the white matter tracts in the brain or the thermal conveyor belts in the ocean. In this paper, we introduce a cohesive advection primitive, called a stream bundle. Whereas traditional ...

Human brain maturation is characterized by the prolonged development of structural and functional properties of large-scale networks that extends into adulthood. However, it is not clearly understood which features change and which remain stable over time. Here, we examined structural connectivity based on diffusion tensor imaging (DTI) in 121 participants between 4 and 40 years of age. DTI dat...

For spherical waves that radiate from a point source in a homogeneous fluid and propagate across a plane boundary into a dissimilar homogeneous fluid, the acoustic field may differ significantly from the geometric acoustic approximation if either the source or receiver is near the interface (in acoustic wavelengths) or if the stationary phase path is near the critical angle. In such cases, the ...

Automation streamlines a previously labor-intensive process and virtually eliminates sampling or labeling errors. The techniques of molecular biology and genetics continue to assist the physician in the diagnosis, prognosis, and treatment of patients with neoplastic diseases.

Introduction False positive connections are an inevitable part of in vivo probabilistic tractography. Due to the probabilistic sampling process, some streamlines generated by tractography algorithms are typically extraneous, and do not accurately reflect the topology of the underlying white matter fasciculus. When tractography is used as a segmentation tool, such as in group contrast studies in...

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